Research

Group Research

The laboratory of Biointerfaces, led by Prof. Paul Cremer, is a multidisciplinary research team that works at the crossroads of biological interfaces, manomaterials, spectroscopy, and microfluidics. Biophysical and analytical studies are tied together through the employment of novel lab-on-a-chip platforms which enable high throughput/low sample volume analysis to be performed with unprecedented signal-to-noise. From neurodegenerative diseases to artificial hip implants, a huge variety of processes occur at biological interfaces. Our laboratory uses a wide variety of surface specific spectroscopies and microfluidic technologies to probe mechanisms of disease, build new biosensors against pathogens, and understand the molecular-level details of the water layer hugging a cell membrane. Research projects in the Cremer Group are divided into the four areas listed below.  Click on your area(s) of interest to learn more.

SFG of water and ions at interfaces

Spectroscopy of Interfaces

Hofmeister Effect of Electrolytes, Osmolytes

Hofmeister Effects on Biomolecules

Bioinorganic Chemistry and Biomaterial Properties of Lipid Bilayers

Bioinorganic Chemistry of Lipid Bilayers

Biosensors

Bilayer Platforms for Biosensors and Separations

Recent Posts

Dr. Cremer is recognized as the 2017 Langmuir Lecturer for his outstanding contributions to the interdisciplinary field of colloid, interfacial and surface chemistry. Congratulations, Paul!

The ACS journal Langmuir in partnership with the Colloid and Surface Chemistry Division (COLL) is proud to announce the selection of Professors Frank Caruso of the University of Melbourne and Paul Cremer of the Pennsylvania State University, as the 2017 Langmuir Lecturers. Professors Caruso and Cremer will be presenting their Langmuir Lectures at the ACS Fall National Meeting, August 20-24, 2017 in Washington, DC.

Professors Frank Caruso and Paul Cremer are the distinguished 2017 Langmuir Lecturers.

Professors Frank Caruso of the University of Melbourne and Paul Cremer of the Pennsylvania State University are recognized as the 2017 Langmuir Lecturers for their outstanding contributions to the interdisciplinary field of colloid, interfacial and surface chemistry.

Paul Cremer, The Pennsylvania State University

Professor Cremer’s presentation will focus on “Probing the Interactions of Anions and Cations with Phospholipid Membranes”.

View selected articles published by Cremer

An NH Moiety is not Required for Anion Binding to Amides in Aqueous Solution Langmuir, 2015, 31(11), pp 3459–3464

DOI: 10.1021/acs.langmuir.5b00127

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Stepwise Molding, Etching, and Imprinting to Form Libraries of Nanopatterned Substrates

Langmuir, 2013, 29 (22), pp 6737–6745

DOI: 10.1021/la400943j

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Specific Anion Effects on Water Structure Adjacent to Protein Monolayers

Langmuir, 2010, 26 (21), pp 16447–16454

DOI: 10.1021/la1015862

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Double Cushions Preserve Transmembrane Protein Mobility in Supported Bilayer Systems

Langmuir, 2008, 24 (13), pp 6820–6826

DOI: 10.1021/la800018d

  1. Anne passed her PhD defense. Congratulations, Dr. Sendecki! Comments Off on Anne passed her PhD defense. Congratulations, Dr. Sendecki!
  2. Spring Semester Group Lunch on April 28th, 2017 Comments Off on Spring Semester Group Lunch on April 28th, 2017
  3. 2017 Spring Group Picture Comments Off on 2017 Spring Group Picture
  4. Group Lunch at The Deli Restaurant Comments Off on Group Lunch at The Deli Restaurant
  5. Chad won “Graduate Student Teaching Award” funded by the “Troxwell Endowment Fund.” Congratulations, Chad! Comments Off on Chad won “Graduate Student Teaching Award” funded by the “Troxwell Endowment Fund.” Congratulations, Chad!
  6. Chris Munson, Susan Daniel, Laura Sagle, Paul Cremer, Hanbin Mao, and Jinjun Shi at SciX in Minneapolis on Sept. 21, 2016 Comments Off on Chris Munson, Susan Daniel, Laura Sagle, Paul Cremer, Hanbin Mao, and Jinjun Shi at SciX in Minneapolis on Sept. 21, 2016
  7. Dr. Paul Cremer receives the ANACHEM Award, Sept. 21, 2016 Comments Off on Dr. Paul Cremer receives the ANACHEM Award, Sept. 21, 2016
  8. Congratulations to the New Bioananlytical Sensors GRC vice-chair Dr. Susan Daniel Comments Off on Congratulations to the New Bioananlytical Sensors GRC vice-chair Dr. Susan Daniel
  9. Congratulations to Virginia, Brad, and Codey for Passing the Comprehensive Exams! Comments Off on Congratulations to Virginia, Brad, and Codey for Passing the Comprehensive Exams!