We Are Hiring a Research Technician and Several Post-Doctoral Scientists, funded by two NIH R01 Awards. See Employment Opportunities Page.

Welcome to the Lindner Laboratory at Penn State in the Department of Biochemistry & Molecular Biology. Simply stated: our work couples molecular parasitology and structural biology to understand the malaria parasite (Plasmodium spp.), so that we can identify and exploit weaknesses in the parasite’s development and transmission.

Follow us on Twitter: @LindnerLab    


Lindner Lab (April 2018)
Front Row (Left-to-Right): Kelly Rios, Trace Besemer, Liv Smith
Back Row (Left-to-Right): Logan Finger, Kevin Hart, Scott Lindner, Allen Minns, Steve Griffin, Mike Walker
Not Pictured: Tyler Earp (now an alumnus!)
New Additions Since April 2018: Joann Butkus, Lauren Sarko, Megan Gragg, Tanumoy Mondol


Latest News for the Lindner Lab (Get the full version at the Lindner Lab News Page)

Kevin Hart‘s manuscript on the deadenylases of the CAF1/CCR4/NOT complex has been editorially accepted for publication in PLoS Pathogens! Congrats to Kevin, Mike, and Allen, and our collaborators in John Adams’ Lab at USF! (20181210)

Tanumoy Mondol has joined the Lindner and Hafenstein Labs here in Happy Valley. Welcome, Tanumoy! (20181201)

Mike Walker‘s manuscript on CRISPR-RGR in Plasmodium yoelii has been posted to Biorxiv. This describes why many groups have had issues with plasmid integration using CRISPR, and also shows that CRISPRi is functional in Plasmodium! https://www.biorxiv.org/content/early/2018/11/29/481416 (20181129)

Megan Gragg has arrived, and will be the newest member of the Lindner and Hafenstein Labs. Welcome, Megan! (20180917)

Lauren Sarko has joined the Lindner Lab as an undergraduate researcher. Welcome, Lauren! (20180820)

Tanumoy Mondol has accepted our offer and will also join the Lindner and Hafenstein Groups as a post-doctoral scientist in December 2018 working on our cryo EM pursuits. Tanumoy has been working with Peter Burgers at Wash U. on PCNA and Pol Delta, and will bring great expertise to our groups. Welcome, Tanumoy! (20180820)

Megan Gragg has accepted our offer and will join the Lindner and Hafenstein Groups as a post-doctoral scientist in September 2018 working on our collaborative cryo EM work. Megan has recently completed her Ph.D. at Case Western Reserve University in Cleveland with Paul Park on biophysical measurements of rhodopsins and pathogenic variants. Welcome aboard, Megan! (20180814)

Trends in Parasitology just accepted our review of the proteomics studies of Plasmodium parasites over the last decade. This was great fun to write with my long-time collaborator, Kristian Swearingen at ISB/CIDResearch in Seattle! (20180805)
Update: We were also selected for the cover for November 2018! See it here.

Joann Butkus has joined the Lindner Lab as a Research Technologist 1. She will be our Mosquito Colony Manager and work to advance new techniques for molecular parasitology applications. Welcome, Joann! (20180604)

The Applied Biological and Biosecurity Research Laboratory (ABRL) at Penn State has launched their website (click here). We partner with ABRL with an interest on malaria transmission in South America (20180605)

Steve Griffin has accepted a position to launch his career after graduating from Penn State. Congrats, Steve! (20180511).

Kelly Rios presented her work on RNA structural analyses for the RNA Club at Penn State. Its great to have so many sharp minds with us to consider this interesting aspect of Plasmodium biology! (20180316)

A collaborative project with Noah Butler (U. Iowa) and Marion Pepper (U. Washington) on cGAS-mediated control of Plasmodium blood stage infections is now out in JCI Insight. (20180125)

Kelly Rios has passed her Comprehensive Exam and is now a Ph.D. Candidate/Dissertator in our BMMB Program. Congrats, Kelly! (20180112)

Allen Minns has published on PABP1 and PABP2 in Plasmodium yoelii in mSphere! This is work done also by Kevin Hart and in collaboration with Susan Hafenstein‘s lab. Congrats, Allen! (20180110)

Liv Smith has joined our research group as an undergraduate researcher, focusing on proximity-based biotinylation approaches for proteomics. Welcome, Liv! (20180108)

I (Scott) received a Notice of Award from NIGMS for our 2nd R01: a Multi-PI R01 with Susan Hafenstein (and Phil Bevilacqua as co-investigator)! This will fund our Cryo-EM efforts for the next 4 years to push the boundaries of what is possible for structural studies of Plasmodium proteins (big or small!). (20171230)


<See Lindner Lab News for More!>



The Lindner Laboratory is housed in the Millennium Science Complex, which brings together a variety of top-notch research groups to build an interdisciplinary, collaborative environment.



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