Koubek, E.J. and L.C. Santy (2016). “ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation.” Small GTPases, 12 Aug 2016: p. 1-18. Pubmed
Salem, J. C., M. M. Reviriego-Mendoza and L. C. Santy (2015). “ARF-GEF cytohesin-2/ARNO regulates R-Ras and alpha5-integrin recycling through an EHD1-positive compartment.” Mol Biol Cell 26(23): 4265-4279. PubMed
Reviriego-Mendoza, M. M. and L. C. Santy (2015). “The cytohesin guanosine exchange factors (GEFs) are required to promote HGF-mediated renal recovery after acute kidney injury (AKI) in mice.” Physiol Rep 3(6): e12442. PubMed
Hiester, K. G. and L. C. Santy (2013). “The Cytohesin Coiled-Coil Domain Interacts with Threonine 276 to Control Membrane Association.” PLoS ONE 8: e82084. PubMed
Attar, M. A. and L. C. Santy (2013). “The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration.” BMC Cell Biol 14: 9. PubMed
Leshner, M., S. Wang, C. Lewis, H. Zheng, X. A. Chen, L. Santy and Y. Wang (2012). PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures. Front. Immun. I 3:307. PubMed
Oh, S. J., and Santy, L. C. (2012) Phosphoinositide specificity determines which cytohesins regulate beta1 integrin recycling. J Cell Sci 125:3195-3201. PubMed
Attar, M. A., Salem, J. C., Pursel, H. S., and Santy, L. C. (2012) CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration. Exp Cell Res 318, 228-237. PubMed
White, D. T., McShea, K. M., Attar, M. A., and Santy, L. C. (2010) GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180. Mol Biol Cell 21, 562-571. PubMed
Oh, S. J., and Santy, L. C. (2010) Differential effects of cytohesins 2 and 3 on beta1 integrin recycling. J Biol Chem 285, 14610-14616. PubMed
Shmuel, M., Santy, L. C., Frank, S., Avrahami, D., Casanova, J. E., and Altschuler, Y. (2006) ARNO through its coiled-coil domain regulates endocytosis at the apical surface of polarized epithelial cells. J Biol Chem 281, 13300-13308. PubMed
Clarke, M., Ewart, M. A., Santy, L. C., Prekeris, R., and Gould, G. W. (2006) ACRP30 is secreted from 3T3-L1 adipocytes via a Rab11-dependent pathway. Biochem Biophys Res Commun 342, 1361-1367. PubMed
Santy, L. C., Ravichandran, K. S., and Casanova, J. E. (2005) The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1. Curr Biol 15, 1749-1754. PubMed
Martinu, L., Masuda-Robens, J. M., Robertson, S. E., Santy, L. C., Casanova, J. E., and Chou, M. M. (2004) The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6. Mol Cell Biol 24, 9752-9762. PubMed
Li, H. S., Shome, K., Rojas, R., Rizzo, M. A., Vasudevan, C., Fluharty, E., Santy, L. C., Casanova, J. E., and Romero, G. (2003) The guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin. BMC Cell Biol 4, 13. PubMed
Santy, L. C. (2002) Characterization of a fast cycling ADP-ribosylation factor 6 mutant. J Biol Chem 277, 40185-40188. PubMed
Santy, L. C., and Casanova, J. E. (2002) GTPase Signaling: Bridging the GAP between ARF and Rho. Curr Biol 12, R360-362. PubMed
Santy, L. C., and Casanova, J. E. (2001) Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D. J Cell Biol 154, 599-610. PubMed
Santy, L. C., Frank, S. R., and Casanova, J. E. (2001) Expression and analysis of ARNO and ARNO mutants and their effects on ADP-ribosylation factor (ARF)-mediated actin cytoskeletal rearrangements. Methods Enzymol 329, 256-264
Santy, L. C., Frank, S. R., Hatfield, J. C., and Casanova, J. E. (1999) Regulation of ARNO nucleotide exchange by a PH domain electrostatic switch. Curr Biol 9, 1173-1176. PubMed
Santy, L. C., and Guidotti, G. (1997) Expression of a single gene produces both forms of skeletal muscle cyclic nucleotide-gated channels. Am J Physiol 273, E1140-1148. PubMed
Santy, L. C., and Guidotti, G. (1996) Reconstitution and characterization of two forms of cyclic nucleotide- gated channels from skeletal muscle. Am J Physiol 271, E1051-1060. PubMed