Adichie @ PSU – Reflection

During her time at Penn State, Adichie said, “I would say, do different things. And I guess I would also say, listen. And I mean that in all kinds of ways. I think that this is a culture and a generation that doesn’t do a lot of listening, and I would say, if possible, listen more than you talk,” when asked about advice to give current freshman students. And I think this is such crucial advice. Firstly, college is a time to reinvent yourself, try new things, and put yourself out there in ways you never even imagined before. This speaks to what she said about doing things differently. You also get the opportunity to meet so many new kinds of people and you can either judge them and dismiss your differences, or embrace them and learn from them. This plays a lot into the second thing she said about listening rather than speaking. This is definitely a huge problem that our generation has, and the first step to overcoming any large issue to recognize it. Next, we have to collectively actually do something about it.

Another thing Adichie said that stuck with me is when she said: “In general, I don’t think any work of art is perfect. Nothing is ever really finished. Creative work by its very nature is unfinished.” Now that I’ve heard it, I completely agree with this statement, but would never have thought of this myself. Art has many forms: drawings, paintings, poems, songs, essays, novels, etc. But each of these things is unique and was created with an equally distinctive purpose. All art forms are subjective and not one can be marked “perfect” or “finished” because beauty is truly in the eye of the beholder. There is a free domain about art; anyone can add to or change any painting or song or story, but doing so never actually changes the original piece.

Lastly, Adichie said, “People would say things to me like, “How did you become like that?” I don’t know I’m even like, this is who I am. If I had to invent an answer to your question, it would be my upbringing, my parents. There’s a sense, growing up in a space where you feel safe, loved, and you’re given… And I think there’s something wonderful about just having the space where you can be who you are. And I think that’s what it is. My sense of self, I think, is very deeply rooted in family, and also, really, in a certain sense, in culture, as well.” This stuck with me because it’s very reminiscent of what I wrote my Common App essay on for college applications! I chose the general prompt and proceeded to write about the people and experiences that have shaped my views and personality, which largely connects to what Adichie says here. I also strongly attributed everything to my parents and the upbringing they gave me, and it was really cool to see Adichie do the same.

It’s been a while…

It’s been a while since the last time we had to blog…and there have been so many incredible things I could’ve blogged about! So to avoid having to pick my “favorite” one, and to include as much information as possible, I’m going to try to give shorter summaries of multiple discoveries.

  1. Legalize: Weed Shrinks Tumors

http://www.iflscience.com/health-and-medicine/how-cannabis-was-used-shrink-one-most-aggressive-brain-cancers

Cannabinoids are the active components of the cannabis plant, and two of them, THC and CBD (tetrahydrocannabinol and cannabidiol), have already been in use for treating things like multiple sclerosis and cancer side-effects. THC is the chemical that gets drug users high, and the psychoactivity it causes in neuro-receptors has been linked to the same receptors in brain tumors.

Brain cancer is one of the most aggressive and has one of the highest mortality rates among cancers. Invasive surgery, chemotherapy, and radiation all together are still no guarantee for a cure. But when combining radtiotherapy with cannabinoid treatment, a big difference could be seen.

The problem of finding the right dosage still exists, however. And with this treatment, it’s is also very possible that the patient could end up being high all the time. Scientists are trying to use amounts of THC below the psychoactive levels, and for now the results are promising.

  1. Clear(ly) Mice

http://www.iflscience.com/health-and-medicine/scientists-make-transparent-mice-study-cellular-connections

Japanese scientists have engineered mice that are completely transparent. This way, internal body structure and functions can be studied. Also, this will enable them to study very fine and delicate cellular connections in vivo. The clear color of the mouse was achieved by removing the heme, which is a part of hemoglobin, from the brain, heart, kidneys, liver, and lungs. Using a direct transcardial perfusion and a two-week cleaning process, the mice became transparent and enabled scientists to see cellular networks within tissues.

This process is done on mice that are already dead. Certain traits from the mice (ie. diabetic or non diabetic) are taken into account and can be observed once the specimen is made transparent. This is a revolutionary feat in the world of pathology and will help to deepen our understandings of the body’s inner workings.

  1. Real-Time Metastasis

http://www.iflscience.com/health-and-medicine/device-gives-real-time-look-cancer-metastasis

In a previous blog I discussed metastasis, or the growth and proliferation of cancer cells from their original site. Metastasis is very deadly and very hard to prevent. This is why two doctors at Johns Hopkins University created an artificial vessel in the lab that allows an ex vivo visualization of the process. There is still so much that is unknown about the process of metastasis and having this device will allow researchers to come to a deeper understanding of it.

By using fluorescent-tagged breast cancer cells into the artificial atmosphere of the device, they were able to observe the growth and spread of the cancer cells. By observing metastasis, we can come to understand it, and by understanding it, we can find a way to stop and cure it and save lives. And that’s really what it’s all about

“I have to give a TED Talk?!”

The first time I heard that we were going to have to give a TED Talk, panic set in. I’ve always been very anxious regarding public speaking, and this took it to a whole new level by being the longest and also the only completely memorized speech I’ve ever given. Somehow, don’t ask how, I pulled this together in a relatively short amount of time considering how long we’ve had this assignment on our radars, and I think it actually turned out pretty well!

After watching the video, I think that the talk itself went well. I did do a one thing slightly out of order because I had forgotten it in the place it should’ve gone, but other than that, I managed to get everything out. I realized that I did use a decent amount of conversational crutches such as “like” and “um,” but that can only go away with practice and more experience. In conversation, I tend to talk with my hands, and now looking at it in a presentation setting, it looks kind of awkward. Pointing at the screen and highlighting things on the powerpoint were fine, but the smaller random gestures I made while speaking look a little uncomfortable and almost distracting. But this also is something that just needs more time and experience to refine.

Going first was absolutely terrifying; I hadn’t seen anyone else’s official talks and had no idea how mine would stack up after the fact. But after presenting, it was so nice and I was able to relax so much more than I would have if I had gone later in the list. To be completely honest, put off picking a topic for so long because I just didn’t know what to do. This was the first idea that really struck me as a big shift that would have substantial facets to talk about. Through this, I found that I was able to talk about the origin, current state of, and even extrapolate to the future of this shift.

Check it out for yourself if you’d like!

Stasis Theory

Stasis, as defined by the RCL textbook, is the ancient theory of planning, executing, and resolving an argument. There are four pillars of stasis that help support and define any given issue or argument. The first is known as Conjecture, which asks about the given situation and what happened. The second is Definition, which explains the meaning behind the event. Third is Quality, which questions the morality of the issue, and fourth is Policy, which asks how to go about resolving the problem at hand. By answering these questions and compiling the knowledge about them, not only can a better understanding of the article be reached, but also a better solution can be achieved.

For the history of a public controversy project, my group has been considering exploring the morality of gun rights as well as the lowering/withholding of the drinking age. Both of these topics are very relevant, not only to today’s society, but also to us as young adults in college. Their societal prevalence provides ample information for the project as well as personal opinions that we all have going into the project as well. Between all of the resources available to us, including each other, we will definitely be able answer the four questions of stasis and come up with a full and thorough argument and project.

HIV + Cancer = good?

http://www.iflscience.com/health-and-medicine/how-notorious-hiv-being-hijacked-tackle-cancer

If you watch Grey’s Anatomy, you probably remember the episode from last season where Bailey used HIV to cure a sick patient. The patient was a young and immunocompromised boy who was stuck in a plastic “bubble” because his immune system was so weak, it was practically nonexistent. The way Dr. Bailey restored this boy’s immune system was by removing the viral DNA from the vector and replacing it with the treatment. Of course, this is a dramatic TV show, so the patient’s parents were enraged that Bailey had gone behind their backs and treated their son without their consent, etc. etc. But at the time, it seemed like such a farfetched treatment that was only happening in a fictional TV show (I mean, they were even trying to 3D print full and functional hearts on there!), but it turns out that this type of treatment isn’t so farfetched after all.

Researchers (in real life!) have started to use and manipulate HIV in the fight against cancer. Cancer is an extremely complicated and diverse disease; there are over 200 types of it and even more within those categories. Seemingly infinite combinations of mutations cause cancer, making the prospect of finding one, universal cure slim to none. However, it has been said that the future of medicine is in personalized treatments. This means things like gene therapy and nanoparticles, which are specially tailored for each individual patient and case. This treatment with HIV is still in very early stages and has only been tentatively used a few times. The media is also very quick to announce things like, “Doctors cure leukemia by injecting girl with HIV,” which is not the whole truth and is extremely misleading. This causes grand misunderstandings among the general population and subsequent outrage in some cases. However, it’s all still a work in progress.

Not only can the HIV vector be used in treating hyper-proliferative diseases like cancer, but it is also being used in research labs. By inserting cancerous DNA into the HIV vector, scientists are able to grow many cancer cells for culture. This is a very good thing because it is difficult to grow and maintain such cells outside of the body. This makes research slighter easier and also more efficient because it gives scientists more time to work instead of having to culture and maintain and small amount of cells.

Although it’s new and still not applicable to all types of cancer, this new method of treatment and research is revolutionary. The world of science is constantly changing and evolving. Who would’ve ever thought that one deadly disease could be used to treat and even cure another even deadlier one? Of course, HIV is still an epidemic and a massive global problem, but if we as humans can exploit it just a to just a fraction of the amount that it exploits us, it’s a pretty cool thing.