Assistant Professor
Director of Genome Sciences Facility
Department: Pharmacology, Biochemistry and Molecular Biology, Institute for Personalized Medicine
Email: yimamura@pennstatehealth.psu.edu
Phone: 7175310003 x289250
Research Interests:
Genomics, Next-Generation Sequencing, Bioinformatics, Neurogenomics, Biomarker, Transccriptome, Exome, DNA methylation, Metagenome, Microbiome, Exosome, Omics, Liquid Biopsy, Single cell genomics, Brain development, Neuroscience, Cancer, Oncology, Molecular Biology, Cell Biology
Systems/Organs:
Brain, neural system, others
Cell/Cellular compartments:
Neurons, others; DNA/RNA, DNA methylation
Signaling pathways:
Transcription
Diseases/Conditions:
Development, Cancer
Research description:
The goal of Dr. Yuka Imamura’s research is to commit herself to support “start-to-finish” genomics project. Dr. Imamura joined Penn State Hershey in August of 2013 following postdoctoral research training at the University of Texas Southwestern, The Rothberg Institute for Childhood Diseases, and Yale University. Her qualifications stems from her own research in neurogenomics and providing next-gen sequencing support in the form of sample preparation, sequencing, and data analysis.
Technical expertise: Genomics, Next-Generation Sequencing, Bioinformatics, Neurogenomics, Biomarker finding, Transccriptome, Exome, DNA methylation, Metagenome, Microbiome, Exosome purification, Omics, Liquid Biopsy, Single cell genomics, Neuroscience, Cell Biology, Biochemistry, Cancer biology, Metabolic disease.
Selected Publications:
- Kawasawa YI, Salzberg AC, Li M, Šestan N, Greer CA, Imamura F. RNA-seq analysis of developing olfactory bulb projection neurons. Mol Cell Neurosci. 2016 Jul;74:78-86.
- Ge Z, Gu Y, Xiao L, Han Q, Li J, Chen B, Yu J, Kawasawa YI, Payne KJ, Dovat S, Song C. Co-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunction. Oncotarget. 2016 Jun 14.
- Clawson GA, Matters GL, Xin P, Imamura-Kawasawa Y, Du Z, Thiboutot DM, Helm KF, Neves RI, Abraham T. Macrophage-Tumor Cell Fusions from Peripheral Blood of Melanoma Patients. PLoS One. 2015; 10(8):e0134320.
- Kang HJ, Kawasawa YI, Cheng F, Zhu Y, Xu X, Li M, Sousa AM, Pletikos M, Meyer KA, Sedmak G, Guennel T, Shin Y, Johnson MB, Krsnik Z, Mayer S, Fertuzinhos S, Umlauf S, Lisgo SN, Vortmeyer A, Weinberger DR, Mane S, Hyde TM, Huttner A, Reimers M, Kleinman JE, Sestan N. Spatio-temporal transcriptome of the human brain. Nature. 2011 Oct 27; 478(7370):483-9.
Related Links: