Dr. David Gilmour

Dr. David Gilmour

Professor

Department: Biochemistry and Molecular Biology
College:  Eberly College of Science
Address: 465 North Frear
Phone: 814-863-8905
E-mail: dsg11@psu.edu
Website: https://www.huck.psu.edu/people/david-gilmour

Transcription compartment targeting.
Transcriptionally active regions of the genome appear as puffs in Drosophila polytene chromosomes. We have evidence that these a phase separated domains and that certain amino acid sequences function to target proteins to these domains. The project will entail making transgenic Drosophila that express putative targeting sequences fused to green fluorescent protein (GFP) and determining if the GFP associates with puffs.