Abstract: Haemophilus ducreyi, the causative agent of chancroid, is a gram-negative bacterium, which has an outer membrane to protect the bacteria from several common antibiotics, such as vancomycin. Research showed that vancomycin is able to affect class II strains...
Abstract: Glucocorticoids are steroid hormones both secreted by the body and administered to patients with inflammatory diseases for their anti-inflammatory properties. Chronic usage of these drugs has been associated with immunosuppression and osteoporosis; chronic...
Abstract: Type IV collagen proteins are structural molecules that form a thin, flexible sheet as part of the basement membrane, which lines our bodily tissues and helps keep them organized. Mutations affecting Type IV collagen proteins can cause disorders such as...
Abstract: The innate immune system of the fruit fly, Drosophila melanogaster, utilizes the IMD and Toll mediated pathways to synthesize antimicrobial peptides (AMPs), which are the first line of defense of the humoral immune response. Other aspects of the Drosophila...
Abstract: I. scapularis ticks can transmit multiple diseases to humans, and understanding interactions between ticks and the pathogens they carry can improve prevention, diagnosis, and treatment of tick-borne illnesses. As in many arthropods, the immune system of I....
Abstract: Polychlorinated biphenyls (PCBs) are contaminants in Lake Erie that travel through food webs eventually making their way into game fish consumed by Erie County residents. There’s a clear correlation between PCB exposure and breast cancer, and Erie...
