Abstract: Diabetes mellitus is a common metabolic disease that can impair osteogenesis through a decrease in osteoblast activity leading to an increased fracture risk. While it is known that diabetes mellitus affects bone, the underlying connection between diabetes...
Abstract: Implantable medical devices (IMDs) have been developed as treatments for disease and to repair injuries or tissue degradation. Risks associated with this technology include complications and infection from implantation surgery. In addition to these risks,...
Abstract: The structural maintenance of chromosomes 5/6 complex is the least understood complex within the Smc protein family. An interesting subunit of this complex within Saccharomyces cerevisiae is Mms21, which is a small ubiquitin-like modifier E3 ligase thought...
Abstract: Epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase that, under normal functioning, undergoes conformational changes due to phosphorylation and participates in the cell’s proliferation and maintenance. Overexpression of...
Abstract: Diabetic retinopathy (DR) is accountable for over 8,000 cases of blindness globally each year. DR affects the retina which is a thin tissue that is made up of ten layers that line the inner surface of the back of the eye. The retina processes information...
Abstract: Ultraviolet Rays (UV) such as UVB are responsible for non-melanoma skin cancer, making up 4-5% of cancers in the United States. DNA breakage caused by UV light is responsible for mutations such as cyclobutane pyrimidine dimers (CPD) that lead to cancer....