Abstract: Diabetes mellitus (DM) is a chronic condition resulting from insulin deficiency or systemic insulin resistance. In this disorder, either the pancreatic β-cells are unable to produce enough insulin, or the secreted insulin is ineffective to overcome the...
Abstract: African Swine Fever Virus (ASFV) is a double-stranded DNA virus that causes severe hemorrhagic fever in domestic swine (Sus scrofa domesticus) which experience a mortality rate approaching 100%. The natural reservoir for ASFV resides in warthogs...
Abstract: In an increasingly globalized world, trade presents numerous opportunities for transmission of infectious agents that not only pose a direct threat to human health but also leverage attacks against our food supply. There is not a single meat type that is...
Abstract: Typically, repeat exposure to identical agents of disease results in a robust immune response that likely leverages neutralizing antibodies. However, for a select few infectious agents, opsonization by host antibodies drives pathogenesis by permitting the...
Abstract: African Swine Fever Virus (ASFV) is especially lethal to pigs, and targets porcine macrophages. No commercial vaccine or treatment exists, and culling infected livestock is the only means of infection control. Vaccines leveraging a humoral strategy of...
