Abstract: Glucocorticoids are steroid hormones that occur in the body in order to maintain metabolic and homeostatic processes. Glucocorticoids can be created synthetically in order to mimic natural glucocorticoids, which can be prescribed to treat various conditions,...
Abstract: Potatoes (Solanum tuberosum) are the world’s fourth most important crop, valued at $3.94 billion as of 2019. Potatoes require the use of sprout inhibitors to suppress growth for long-term storage. Sprouting tubers have a decreased value due to spoilage...
WITHDRAWN Abstract: Estrogen (E2) is the cholesterol derived female sex hormone, which is subsequently produced in much higher concentrations in females than males. It has inflammatory effects at low concentrations, but when it is in high concentrations such as during...
Abstract: Colorectal cancer is a debilitating disease driven by many unique mutations. One frequently mutated gene is Adenomatous Polyposis Coli (APC). The APC gene encodes a protein that is essential for the destruction of (Beta)-catenin, the effector protein of the...
Abstract: The KRAS oncogene encodes a GTPase that mediates cell proliferation. The KRAS G12C allele is a missense substitution detected in 19% of human cancer cells (Cekani, 2022). Clinically, KRAS G12C blockers have been recently approved for the treatment of...
Abstract: The mutant allele KRAS G12C is one of the most frequently mutated alleles across all cancer types. Once considered undruggable, decades of pharmacological research have identified mutation-specific drugs that target not only KRAS G12C but also other oncogene...
