Abstract: Infectious agents underly the cause of approximately 15% of all cancers. The majority of these infectious agents are viruses, and few vaccines exist for such oncoviruses. In sub-Saharan Africa, the prevalence of Kaposi Sarcoma Herpes Virus (KSHV) within the...
Abstract: The Global Cancer Observatory (GCO) is administered by a special arm of the World Health Organization (WHO) for cancer surveillance. GCO tracks epidemiological burden of numerous cancer types via annual initiatives known as GLOBOCAN. For example, of the 14...
Abstract: Kaposi sarcoma herpesvirus (KSHV), also known as human herpesvirus-8 (HHV-8), is a non-integrating oncovirus that causes a wide spectrum of malignancies or disorders, including Castleman Disease (CD), Kaposi Sarcoma (KS), and Primary Effusion Lymphoma (PEL)....
Abstract: Viruses are notorious for their ability to infect their host and surpass host immune systems. Although the human immunological system is advanced and many viral infections last for only a short period of time, there are certain viral invaders that are...
Abstract: The KRAS oncogene encodes a GTPase that mediates cell proliferation. KRAS mutations are common drivers of cancer. The KRAS G12C allele is a missense substitution of cysteine for a glycine. This allele accounts for about 44% of all KRAS mutations. ARS1620 and...
