We harness two fundamental sources of energy, light and sound, to image structural, functional and molecular information of living subjects. Medical devices using optical and ultrasound technologies are non-ionizing (safe), cost-effective, not bulky (e.g., portable for mobile health), and can be realized in various forms, including wearable devices for continuous health monitoring. We approach/solve an imaging problem by developing and integrating imaging principles (theory), instrumentation (hardware), and image reconstruction algorithms (software).
We develop novel imaging tools based on optical, ultrasound, and photoacoustic technologies for pre-clinical and clinical translation applications in neurological/cancer/cardiovascular diseases. These tools include multi-scale imaging devices (e.g., microscopes, macroscopes, and endoscopes) and molecular specific approaches to image features as small as organelles and as big as organs.