We are very excited to announce a new MPI R01 grant from the NCI awarded to Dr. Nadine Hempel (Penn State) and Dr. Mythreye Karthikeyan (University of South Carolina), and including a collaboration with Dr. Rebecca Phaeton.
The study focuses on the Role of SOX2 in Stress Adaptations to Ovarian Cancer Anchorage Independence.
Check out some of their past collaborative work:
Worley BL, Kim YS, Mardini J, Zaman R, Leon KE, Vallur PG, Nduwumwami A,
Warrick JI, Timmins PF, Kesterson JP, Phaëton R, Lee NY, Walter V, Endres L,
Mythreye K, Aird KM, Hempel N. GPx3 supports ovarian cancer progression by
manipulating the extracellular redox environment. Redox Biol. 2018 Nov 17. pii:
S2213-2317(18)30891-7. doi: 10.1016/j.redox.2018.11.009. [Epub ahead of print]
PubMed PMID: 30509602.
Singh P, Jenkins LM, Horst B, Alers V, Pradhan S, Kaur P, Srivastava T, Hempel
N, Győrffy B, Broude EV, Lee NY, Mythreye K. Inhibin Is a Novel Paracrine Factor
for Tumor Angiogenesis and Metastasis. Cancer Res. 2018 Jun 1;78(11):2978-2989.
doi: 10.1158/0008-5472.CAN-17-2316. Epub 2018 Mar 13. PubMed PMID: 29535220.
Kim YS, Gupta Vallur P, Phaëton R, Mythreye K, Hempel N. Insights into the
Dichotomous Regulation of SOD2 in Cancer. Antioxidants (Basel). 2017 Nov 3;6(4).
pii: E86. doi: 10.3390/antiox6040086. Review. PubMed PMID: 29099803; PubMed
Central PMCID: PMC5745496.
Leave a Reply
You must be logged in to post a comment.