Ongoing Projects
USDA 2015-67015-23358 Harvatine (PI) 05/01/2015-04/30/2020
USDA NIFA AFRI
Title: Increasing efficiency of milk synthesis by understanding the regulation of the circadian rhythm of the mammary gland.
The goal of this study was to characterize the circadian pattern of milk synthesis in the dairy cow and determine nutritional factors entraining the mammary clock as well as the role of the mammary clock as a physiological adaptation to reduce stress.
USDA 2015-09175 Harvatine (PI) 02/01/2016-01/31/2019
USDA NIFA AFRI
Title: Determination of altered rumen fermentation by real-time rumination observation.
Rumination observation systems are modern activity sensors that monitor feeding and rumination activity. The project focuses on characterizing the relationship between rumination and milk fatty acid profile and yield.
Nonprofit Grant Harvatine (coPI) 2015-2017
PA Poultry Industry Research Check-off Program
Title: Can Lowering Linoleic Acid Content in the Diets of Laying Hens and Broilers Further Enhance the Conversion of α-Linolenic Acid to the “Heart Healthy” Very Long-Chain Omega-3 Polyunsaturated Fatty Acids in Table Eggs and Poultry Meat?
The goal of the project is to investigate the effect of linoleic acid on inhibition of fatty acid elongase and desaturase enzymes in chickens.
PSU 196698 Harvatine (PI) 04/01/2017-03/01/2018
Micronutrients Inc.
Title: Effect of IntelliBond Minerals on Risk of Diet-Induced Milk Fat Depression in Dairy Cows
Milk fat depression results from a change in the rumen microbial populations caused by dietary factors. The goal of the project is to investigate the effect of copper, magnesium, and zinc hydroxy supplements compared to sulfate minerals on risk of milk fat depression.
000192677 Harvatine (PI) 02/15/2017-03/01/2018
PA Soybean Board
Title: Decreasing Risk of Rumen Upset and Low Milk Fat by Feeding High Oleic Soybeans
The goal of the project is to investigate the risk of shifting the microbial population and causing reduced milk fat synthesis while feeding soybeans genetically selected for a very high oleic acid content.
Completed Projects
178841 Harvatine (PI) 11/01/15-12/31/16
Novus International
Title: Efficacy of milk-based biomarkers to predict increase in microbial protein yield due to 2-hydroxy-4-methylthio-butanoic acid supplementation.
The goal of the project was to investigate the effect of the methionine analog 2-hydroxy-4-methylthio-butanoic acid on modifying the rumen microbial population and decreasing the risk for changes associated with diet-induced milk fat depression.
R2015-11 Harvatine (PI) 02/09/15-09/01/16
Pennsylvania Soybean Board
Title: Effect of high oleic soybean oil on omega-3 fatty acid elongation and incorporation into eggs
Investigated the interaction of oleic and linolenic acid on enrichment of eggs with very long-chain omega-3 fatty acids.
PSU 163779 Harvatine (PI) 06/01/14-12/31/15
Kemin International
Title: Long-term supplementation of KemTRACE CrPr for lactating cows
Investigated the effect of chromium supplementation during lactation on product parameters. Chromium may modify insulin regulation in the cow.
NIH 1R03HD068661-01A1 Harvatine (PI) 03/01/12-02/28/15
Title: The functional role of Spot 14 gene in dietary regulation of milk fat synthesis
The goal of this project was to characterize the milk fat phenotype of the Spot 14 (S14) null mouse. Specifically, we investigated the role of S14 in milk fat response to dietary fat concentration and FA profile, time of day, and short-term feed restriction.
2010-65206-20723 Harvatine (PI) 04/15/10-04/14/15
USDA Agriculture and Food Research Initiative Competitive Grant
Title: The functional role of SREBP1c and S14 in regulation of mammary lipid synthesis by rumen-derived bioactive fatty acids
The goal of this project was to determine the mechanism of milk fat depression in the dairy cow. The grant utilized both bovine and mouse models.