Our cross-disciplinary research agenda is at the interface of biomedical engineering, materials science, applied mathematics, and chemistry. We are interested in mathematical modeling and experimental characterization of a broad class of active biological and synthetic systems where metabolism and other non-equilibrium processes lead to the onset of self-organization and collective behavior. These active systems are exemplified by interacting self-propelled organisms or synthetic agents, from molecular motors to living bacteria, motile cells, bird flocks and even robotic swarms. Despite the simplicity of individual interactions between the constituents, large assemblies of self-propelled agents exhibit fascinating collective motion. The research ranges from mathematical modeling of cell motility and collective cell migration, experimental and theoretical studies of active biocomposites represented by swimming bacteria and biological liquid crystals, to the design of active ink for 3D printing.