Checkout Vengadesh’s recent paper describing the role of Gbetagamma-GRK2 signaling in inflammatory signaling in early OA, a major involvement of macrophage polarization. Congratulations to Vengadesh and the Team!

Early Gβγ-GRK2 Inhibition Ameliorates Osteoarthritis Development by Simultaneous Anti-Inflammatory and Chondroprotective Effects