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Sandra Bennink, Andreas von Bohl, Che J. Ngwa, Leonie Henschel, Andrea Kuehn, Nicole Pilch, Tim Weißbach, Alina N. Rosinski, Matthias Scheuermayer, Urska Repnik, Jude M. Przyborski, Allen M. Minns, Lindsey M. Orchard, Gareth Griffiths, Scott E. Lindner, Manuel Llinás, Gabriele Pradel
A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum
www.plospathogens.org
www.plospathogens.org
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1.6498 0 Td
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1.2019 0 Td
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q
1 j
1 J
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7.4999 0 0 6.6659 377.1779 510.7464 cm
BT
/F7 1 Tf
1 TL
-0.0053 Tc
0 0 Td
(3)Tj
ET
Q
q
1 j
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BT
/F7 1 Tf
1 TL
-0.004 Tc
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3.3618 0 Td
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[()4()4()10()6()4()12()12( )12()]TJ
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5.1306 0 Td
([)Tj
0.83 0.64 0.02 0 k
(20)Tj
0 g
(,)Tj
0.83 0.64 0.02 0 k
(21)Tj
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(].)Tj
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(female)Tj
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(gametocytes,)Tj
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(where)Tj
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(it)Tj
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(crucial)Tj
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(synthesis)Tj
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(onset)Tj
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(gametogenesis.)Tj
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Q
q
1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 339.0236 cm
BT
/F3 1 Tf
1 TL
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/F14 1 Tf
0 -1.5023 Td
(7-Helix-1)Tj
4.1433 0 Td
(shares)Tj
2.8347 0 Td
(homologies)Tj
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(with)Tj
2.0787 0 Td
(LanC-like)Tj
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(protein)Tj
3.3072 0 Td
(2)Tj
ET
Q
q
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BT
/F7 1 Tf
1 TL
-0.004 Tc
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(In)Tj
1.1055 0 Td
(order)Tj
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1.0262 0 Td
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(potential)Tj
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(.)Tj
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0.9978 0 Td
[(\n)9()11()4()1()10()4()]TJ
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[(\r)-9( )12()]TJ
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1.8878 0 Td
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(described)Tj
4.0535 0 Td
(SR1,)Tj
2.0182 0 Td
(10,)Tj
1.3947 0 Td
(12)Tj
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(and)Tj
1.7291 0 Td
(25)Tj
1.1736 0 Td
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(22)Tj
0 g
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(we)Tj
1.3266 0 Td
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(a)Tj
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2.0806 0 Td
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(a)Tj
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(putative)Tj
3.4413 0 Td
(GPCR)Tj
-34.1119 -1.3039 Td
(\(PF3D7_0525400\),)Tj
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(henceforth)Tj
4.5581 0 Td
(termed)Tj
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(7-Helix-1.)Tj
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2.0806 0 Td
[()6()15()12()]TJ
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3.6737 0 Td
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(a)Tj
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(55.7)Tj
1.8708 0 Td
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(predicted)Tj
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3.6794 0 Td
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(Fig)Tj
1.8141 0 Td
(1A)Tj
0 g
(\).)Tj
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1.0204 0 Td
(7-Helix-1)Tj
4.0309 0 Td
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1.4456 0 Td
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(e.g.)Tj
1.559 0 Td
(the)Tj
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1.4684 0 Td
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(species)Tj
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2.9991 0 Td
[()]TJ
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(.)Tj
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0.9921 0 Td
[()-13()15()3()]TJ
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(and)Tj
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1.7291 0 Td
[()]TJ
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(.)Tj
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0.9978 0 Td
[()4()2(\r)6()-2()6()2()]TJ
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3.0274 0 Td
(\(putative)Tj
3.7814 0 Td
(GPCRs)Tj
-32.6152 -1.2983 Td
(comprising)Tj
4.7678 0 Td
(a)Tj
0.652 0 Td
(LanCL)Tj
2.9423 0 Td
(domain\),)Tj
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3.8891 0 Td
[()31()11()6()]TJ
2.6646 0 Td
[()-3()12()11()4()2()]TJ
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3.0273 0 Td
(\(hLanCL1)Tj
4.286 0 Td
(and)Tj
1.7291 0 Td
(hLanCL2\),)Tj
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4.5128 0 Td
[()29( )-4()]TJ
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[()18( )-4()-3()1( )4()12( )-4()]TJ
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(\(mLanCL1)Tj
4.575 0 Td
(and)Tj
1.7292 0 Td
(mLanCL2\))Tj
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(and)Tj
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[()30(\r)20()22()11()4()4()11()7()10()-4()]TJ
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[()10()6()11()12()4()16()6()]TJ
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3.5149 0 Td
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3.1521 0 Td
(GCR2\))Tj
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(25)Tj
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()Tj
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(28)Tj
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(7-Helix-1)Tj
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(being)Tj
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(only)Tj
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(exception,)Tj
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