Publications

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

The Exon Junction Complex Factor RBM8A in Glial Fibrillary Acid Protein-Expressing Astrocytes Modulates Locomotion Behaviors. 

Asthana S, Mott J, Tong M, Pei Z, Mao Y.

Cells. 2024 Mar 13;13(6). doi: 10.3390/cells13060498.

 

Single-cell and spatial transcriptomics reveals that PTPRG activates the m(6)A methyltransferase VIRMA to block mitophagy-mediated neuronal death in Alzheimer’s disease. 

Zou D, Huang X, Lan Y, Pan M, Xie J, Huang Q, Zeng J, Zou C, Pei Z, Zou C, Mao Y, Luo J.

Pharmacol Res. 2024 Mar;201:107098. doi: 10.1016/j.phrs.2024.107098. PubMed PMID: 38325728.

 

Emerging role of artificial intelligence in diagnosis, classification and clinical management of glioma. 

Luo J, Pan M, Mo K, Mao Y, Zou D.

Semin Cancer Biol. 2023 Jun;91:110-123. doi: 10.1016/j.semcancer.2023.03.006.

 

Transcriptomic Analyses of Brains of RBM8A Conditional Knockout Mice at Different Developmental Stages Reveal Conserved Signaling Pathways Contributing to Neurodevelopmental Diseases. 

McSweeney C, Chen M, Dong F, Sebastian A, Reynolds DJ, Mott J, Pei Z, Zou J, Shi Y, Mao Y.

Int J Mol Sci. 2023 Feb 27;24(5). doi: 10.3390/ijms24054600.

 

Diverse Roles of the Exon Junction Complex Factors in the Cell Cycle, Cancer, and Neurodevelopmental Disorders-Potential for Therapeutic Targeting. 

Martin H, Rupkey J, Asthana S, Yoon J, Patel S, Mott J, Pei Z, Mao Y.

Int J Mol Sci. 2022 Sep 8;23(18). doi: 10.3390/ijms231810375. 

 

Molecular Insights and Prognosis Associated With RBM8A in Glioblastoma.

Wei L, Zou C, Chen L, Lin Y, Liang L, Hu B, Mao Y, Zou D.

Front Mol Biosci. 2022;9:876603. doi: 10.3390/ijms231810375.

 

The Physiological Roles of the Exon Junction Complex in Development and Diseases. 

Asthana S, Martin H, Rupkey J, Patel S, Yoon J, Keegan A, Mao Y.

Cells. 2022 Apr 1;11(7). doi: 10.3390/cells11071192.

 

Dissecting Molecular Genetic Mechanisms of 1q21.1 CNV in Neuropsychiatric Disorders.

Yoon J, Mao Y.

International Journal of Molecular Sciences, 2021. 22(11):5811. doi: 10.3390/ijms22115811

 

Schizophrenia risk ZNF804A interacts with its associated proteins to modulate dendritic morphology and synaptic development.

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Molecular Brain,  2021. 14, Article number: 12 DOI: 10.1186/s13041-021-00729-2

 

Full function of exon junction complex factor, Rbm8a, is critical for interneuron development. 

McSweeney C, Dong F, Chen M, Vitale J, Xu L, Crowley N, Luscher B, Zou D, Mao Y.

Transl Psychiatry. 2020 Nov 5;10(1):379. doi: 10.1038/s41398-020-01065-0. 

 

Comprehensive analysis of biological networks and the eukaryotic initiation factor 4A-3 gene as pivotal in hepatocellular carcinoma.

Lin Y, Liang R, Mao Y, Ye J, Mai R, Gao X, Liu Z, Wainwright T, Li Q, Luo M, Ge L, Li Y, Zou D. 
J Cell Biochem. 2020 Oct;121(10):4094-4107. doi: 10.1002/jcb.29596. 

 

Rapid Size-Based Isolation of Extracellular Vesicles by Three-Dimensional Carbon Nanotube Arrays. 

Yeh YT, Zhou Y, Zou D, Liu H, Yu H, Lu H, Swaminathan V, Mao Y*, Terrones M*.

ACS Appl Mater Interfaces. 2020 Mar 18;12(11):13134-13139. doi: 10.1021/acsami.9b20990. 

 

Identification of molecular correlations of RBM8A with autophagy in Alzheimer’s disease. 

Zou D, Li R, Huang X, Chen G, Liu Y, Meng Y, Wang Y, Wu Y*, Mao Y*.

Aging (Albany NY). 2019 Dec 9;11. doi: 10.18632/aging.102571. 

 

Expression and gene regulation network of RBM8A in hepatocellular carcinoma based on data mining. 

Lin Y, Liang R, Qiu Y, Lv Y, Zhang J, Qin G, Yuan C, Liu Z, Li Y, Zou D, Mao Y *.

Aging (Albany NY). 2019 Jan 22;11(2):423-447. doi: 10.18632/aging.101749.

 

Systematic Analysis of Gene Expression Alteration and Co-Expression Network of Eukaryotic Initiation Factor 4A-3 in Cancer.

Lin Y, Zhang J, Cai J, Liang R, Chen G, Qin G, Han X, Yuan C, Liu Z, Li Y, Zou D*, Mao Y*.

J Cancer 2018; 9(24):4568-4577. doi: 10.7150/jca.27655.

 

Self-Assembly of Extracellular Vesicle-like Metal-Organic Framework Nanoparticles for Protection and Intracellular Delivery of Biofunctional Proteins.

Cheng G, Li W, Ha L, Han X, Hao S, Wan Y, Wang Z, Dong F, Zou X, Mao Y, Zheng SY.

Journal of the American Chemical Society. 2018; 140(23):7282-7291.  doi: 10.1021/jacs.8b03584.

 

Control of CNS functions by RNA-binding proteins in neurological diseases.

Zhou Y, Dong F, Mao Y*.

Current pharmacology reports. 2018; 4(4):301-313. doi: 10.1007/s40495-018-0140-7

 

Light-Emitting Transition Metal Dichalcogenide Monolayers under Cellular Digestion.

Yeh YT, Tang Y, Lin Z, Fujisawa K, Lei Y, Zhou Y, Rotella C, Elías AL, Zheng SY, Mao Y, Liu Z, Lu H, Terrones M.

Advanced materials. 2018; 30(8). doi: 10.1002/adma.201703321.

 

Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment.

Zhou Y, Dong F, Lanz T, Reinhart V, Li M, Liu L, Zou J, Xi H, Mao Y*.

Molecular Psychiatry. 2018; 23(4):952-962. doi: 10.1038/mp.2017.166.

News at:

https://www.sciencedaily.com/releases/2017/09/170925104711.htm

https://www.medicalnewstoday.com/articles/319557.php

 

Displacement and Hybridization Reactions in Aptamer-functionalized Hydrogels for Biomimetic Protein Release and Signal Transduction.

Lai J, Li S, Shi X, Coyne J, Zhao N, Dong F, Mao Y and Wang Y.

Chemical Science. 2017; 8(11):7306-7311. doi: 10.1039/c7sc03023a

A prenatal interruption of DISC1 function in the brain exhibits a lasting impact on adult behaviors, brain metabolism, and interneuron development.

Deng D, Jian C, Lei L, Zhou Y, McSweeney C, Dong F, Shen Y, Zou D, Wang Y, Wu Y, Zhang L, Mao Y*.

Oncotarget. 2017; 8(49):84798-84817. doi: 10.18632/oncotarget.21381.

Polycistronic tRNA and CRISPR guide-RNA enables highly efficient multiplexed genome engineering in human cells.

Dong F, Xie K, Chen Y, Yang Y*, Mao Y*.

Biochemical and Biophysical Research Communications.  2017. 482:889-895. doi: 10.1016/j.bbrc.2016.11.129.

Transient enhancement of proliferation of neural progenitors and impairment of their long-term survival in p25 transgenic mice.
Zou D, Zhou Y, Liu L, Dong F, Shu T, Zhou Y, Tsai LH, Mao Y*.
Oncotarget. 2016. 7:39148-39161. doi: 10.18632/oncotarget.9834. PMID: 27283769

Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects.
Dong F, Jiang J, McSweeney C, Zou D, Liu L, Mao Y*.
Hum Mol Genet. 2016.  25:2738-2751. PMID: 27131348. doi: 10.1093/hmg/ddw131.

Opposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling.
Boccitto M, Doshi S, Newton IP, Nathke I, Neve R, Dong F, Mao Y, Zhai J, Zhang L, Kalb R.
Neuroscience. 2016; 326:22-30. PMID: 27026592.  doi: 10.1016/j.neuroscience.2016.03.048.

DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction
Zou D , Chen L , Deng D ,  Jiang D,  Dong F,  McSweeney C,  Zhou Y,  Liu L,  Chen G,  Wu Y  and Mao Y*.
Curr Mol Med. 2016;16(1):91-102.  PMID:26733123. doi: 10.2174/1566524016666151222150024.
A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.
Zou D, McSweeney C, Sebastian A, Reynolds DJ, Dong F, Zhou Y, Deng D, Wang Y, Liu L, Zhu J, Zou J, Shi Y, Albert I, Mao Y*.
Neural Dev. 2015 Jun 21;10(1):18. doi: 10.1186/s13064-015-0045-7. PubMed PMID: 26094033; PubMed Central PMCID: PMC4479087. doi: 10.1186/s13064-015-0045-7.
The GluN2B subunit of N-methy-D-asparate receptor regulates the radial migration of cortical neurons in vivo.
Jiang H, Jiang W, Zou J, Wang B, Yu M, Pan Y, Lin Y, MaoY, Wang Y.
Brain Res. 2015 Jun 12;1610:20-32. doi: 10.1016/j.brainres.2015.03.031.

 

Applying stereotactic injection technique to study genetic effects on animal behaviors.
McSweeney C, Mao Y*.
J Vis Exp. 2015 May 10;(99). doi: 10.3791/52653. PubMed PMID: 25992973.

 The applications of  pharmacogenetics in treatment of neurological diseases.  
Gilman C.,  McSweeney C., Mao Y*. 
Curr Mol Med., 2014, 14:880-890. doi: 10.2174/1566524014666140811115900.
 
An EJC factor RBM8a Regulates Anxiety Behaviors.
Alachkar A, Jiang D, Harrison M, Zhou Y, Chen G, Mao Y*
Curr Mol Med. 2013, 13:887-899. doi: 10.2174/15665240113139990019. 

The PP2A-Aβ gene is regulated by multiple transcriptional factors including Ets-1, SP1/SP3, and RXRα/β.
Liu J, Ji W, Sun S, Zhang L, Chen HG, Mao Y, Liu L, Zhang X, Gong L, Deng M, Chen L, Han WJ, Chen PC, Hu WF, Hu X, Woodward Z, Liu WB, Xiao YM, Liang SP, Liu Y, Liu SJ, Li DW
Curr Mol Med. 2012 Sep . 12(8):982-94.  doi: 10.2174/156652412802480916.

Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development.
Singh KK, De Rienzo G, Drane L, Mao Y, Flood Z, Madison J, Ferreira M, Bergen S, King C, Sklar P,Sive H, Tsai LH
Neuron. 2011 Nov 17. 72(4):545-58.  doi: 10.1016/j.neuron.2011.09.030.

Gab2 promotes Colony Stimulating Factor-1 regulated macrophage expansion via alternate effectors at different stages of development.
Lee AW, Mao Y , Penninger JM, Yu S
Mol Cell Biol. 2011 31:4563-81. doi: 10.1128/MCB.05706-11.

Disc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis.
De Rienzo G, Bishop JA, Mao Y, Pan L, Ma TP, Moens CB, Tsai LH, Sive H
FASEB J. 2011 25:4184-97. doi: 10.1096/fj.11-186239.

Dixdc1 is a critical regulator of DISC1 and embryonic cortical development.
Singh KK, Ge X, Mao Y, Drane L, Meletis K, Samuels BA, Tsai LH
Neuron. 2010 Jul 15. 67(1):33-48. doi: 10.1016/j.neuron.2010.06.002.

A novel pathway regulates memory and plasticity via SIRT1 and miR-134.
Gao J, Wang WY, Mao YW, Gräff J, Guan JS , Pan L, Mak G, Kim D, Su SC, Tsai LH
Nature. 2010 Aug 26. 466(7310):1105-9. doi: 10.1038/nature09271.

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.
Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C, Berry EM, Soda T , Singh KK,Biechele T, Petryshen TL, Moon RT, Haggarty SJ , Tsai LH
Cell. 2009 Mar 20. 136(6):1017-31. doi: 10.1016/j.cell.2008.12.044.

Measurement of dissociation rate of biomolecular complexes using CE.
Yang P, Mao Y, Lee AW, Kennedy RT
Electrophoresis. 2009 Feb . 30(3):457-64. doi: 10.1002/elps.200800397.

Cloning of differential expression fragments in cauliflower after Xanthomonas campestris inoculation.
Gu Y, Mao YW, Wang CG, Zhao QC, Sun DL, Song WQ.
Biologia Plantarum. 2008, 52: 462-468

Multiplexed detection of protein-peptide interaction and inhibition using capillary electrophoresis.
Yang P, Whelan RJ, Mao Y, Lee AW, Carter-Su C, Kennedy RT
Anal Chem. 2007 Feb 15. 79(4):1690-5. doi: 10.1021/ac061936e.

A novel role for Gab2 in bFGF-mediated cell survival during retinoic acid-induced neuronal differentiation.
Mao Y, Lee AW
J Cell Biol. 2005 Jul 18. 170(2):305-16. doi: 10.1083/jcb.200505061.

Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation.
Li DW, Liu JP, Mao YW, Xiang H, Wang J, Ma WY, Dong Z, Pike HM, Brown RE, Reed JC
Mol Biol Cell. 2005 Sep . 16(9):4437-53. doi: 10.1091/mbc.e05-01-0010.

Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway.
Wang J, Feng H, Huang XQ, Xiang H, Mao YW, Liu JP, Yan Q, Liu WB, Liu Y, Deng M, Gong L, Sun S,Luo C, Liu SJ, Zhang XJ, Liu Y, Li DW
J Biol Chem. 2005 Jun 17. 280(24):22776-87. doi: 10.1074/jbc.M500032200.

Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epithelium-derived growth factor and downstream genes.
Feng H, Xiang H, Mao YW, Wang J, Liu JP, Huang XQ, Liu Y, Liu SJ, Luo C, Zhang XJ, Liu Y, Li DW
Oncogene. 2004 Sep 23. 23(44):7310-21. doi: 10.1038/sj.onc.1208041.

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis.
Mao YW, Liu JP, Xiang H, Li DW
Cell Death Differ. 2004 May . 11(5):512-26.  doi: 10.1038/sj.cdd.4401384.

Expression and activity of the signaling molecules for mitogen-activated protein kinase pathways in human, bovine, and rat lenses.
Li DW, Liu JP, Wang J, Mao YW, Hou LH
Invest Ophthalmol Vis Sci. 2003 Dec . 44(12):5277-86. doi: 10.1167/iovs.03-0348.

Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway.
Xiang H, Wang J, Mao Y, Liu M, Reddy VN, Li DW
Oncogene. 2002 May 23. 21(23):3784-91. doi: 10.1038/sj.onc.1205455.

Human bcl-2 gene attenuates the ability of rabbit lens epithelial cells against H2O2-induced apoptosis through down-regulation of the alpha B-crystallin gene.
Mao YW, Xiang H, Wang J, Korsmeyer S, Reddan J, Li DW
J Biol Chem. 2001 Nov 16. 276(46):43435-45. doi: 10.1074/jbc.M102195200.

Caspase-3 is actively involved in okadaic acid-induced lens epithelial cell apoptosis.
Li DW, Xiang H, Mao YW, Wang J, Fass U, Zhang XY, Xu C
Exp Cell Res. 2001 Jun 10. 266(2):279-91.  doi: 10.1006/excr.2001.5223.

hTERT can function with rabbit telomerase RNA: regulation of gene expression and attenuation of apoptosis.
Xiang H, Wang J, Mao YW, Li DW
Biochem Biophys Res Commun. 2000 Nov 30. 278(3):503-10. doi: 10.1006/bbrc.2000.3834.

 

 

Construction of a DNA library from chromosome 4 of rice (Oryza sativa) by microdissection.

Mao YW, Liang SY, Song WQ, Li XL, Chen RY
Cell Res. 1998 Dec . 8(4):285-93. doi: 10.1038/cr.1998.28.

Book Chapter

  1. QIN YAN, YING-WEI MAO, DAVID W. LI.  Protein Serine/ Threonine Phosphatases in the nervous System. Encyclopedia of Neuroscience. P3325-3329
  2. Li, DW ; Gong, LL; Deng, M ; Liu, JP ; Liu, MG ; Mao, YW. THE TWO LENS STRUCTURE PROTEINS, alpha A-CRYSTALLIN (HspB4) AND alpha B-CRYSTALLIN (HSPB5), CONTROL APOPTOSIS THROUGH REGULATION OF MULTIPLE SIGNALING TRANSDUCTION PATHWAYS. Protein Science and Engineering. 89-116. 2010

 

Conference Proceeding Paper

Mingda Zhou, Si-jie Hao, Gong Cheng, Xu Yu, Ying-wei Mao, and Si-yang Zheng. INTEGRATED MICRODEVICE FOR SINGLE-NEURON IN VIVO ELECTROPORATION. The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) 

 

Patent

 Tsai L, Mao Y, Madison J, Haggarty SJ. , inventors. DISC-1 PATHWAY ACTIVATORS IN THE CONTROL OF NEUROGENESIS. USA 8263547. 2012 September 11.

 

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