Project Team
Students
Aaron Dominick
Engineering Science
Penn State New Kensington, Penn State University Park
Faculty Mentors
Ibrahim Ozbolat
Penn State University Park
Engineering Science and Mechanics
Project
https://sites.psu.edu/mcreu/files/formidable/2/Array-AAB-Poster.pdf
Project Video
Project Abstract
Aspiration-assisted bioprinting (AAB) is a type of three-dimensional (3D) bioprinting that utilizes aspiration forces to precisely bioprint a wide range of biologics in both scaffold-based and scaffold-free arrangements. It has a wide range of future applications ranging from organ-on-a-chip devices, regenerative medicine, and the study of fundamental biological phenomena. However, the current AAB model is not time efficient, placing only a singular biologic at a time. To improve upon the design and increase efficiency, an array of micropipettes will be employed to print the biologics in a layer-by-layer manner while still allowing for individual valve control. The software side was created using a combination of processing and Arduino that allows for precise control over the movement of the printer, manual activation of valves, and pressure monitoring at the location of the biologic. The hardware side is overseen by an Arduino Due microprocessor that modulates the system through connections with stepper motors, logic level MOSFETS, and a Sparkfun BME 280 Atmospheric Sensor. Overall construction and testing are still underway, but the initial results show promise. Once every system is completely integrated, the array based AAB will offer a time efficient, cost effective, and highly precise bioprinting technique.
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