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Precision Therapeutics and Bioresponsive Materials Lab

Welcome to the Medina Group at Penn State!

Working at the interface of chemical biology and nanomedicine, WE ARE developing advanced tools that can open new opportunities in precision medicine.

Protein Delivery Work Highlighted

Our work on ultrasound-guided protein delivery in tissues has been highlighted by Penn State News, Phys.org and Science Daily!

Matthew Aronson receives NSF GRFP!

Matthew Aronson has recently been named a recipient of the National Science Foundation - Graduate Research Fellowship! This prestigious award will support Matthew as he applies his passions in biomaterial design towards tackling challenges in microbiome engineering...

Matthew Aronson and Bailey Klein defend honors thesis

Congratulations to Matthew Aronson and Bailey Klein, who both successfully defended their honors undergraduate thesis in Spring of 2020. You both did an outstanding job, and I couldn't be prouder of your achievements. The entire Medina lab wishes you well in your...

New Paper in ACS Nano!

Janna's paper describing a new method for ultrasound-guided intracellular protein delivery has been published in ACS Nano, titled: "Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks."

New Paper in PLoS One!

Atip's paper on anticancer lectins has been accepted for publication in PLoS One, titled: "Discovery of antitumor lectins from rainforest tree root transcriptomes."  

Matthew Aronson conducts summer research in Germany

Matthew Aronson completes his global research experience at the Technical University of Kaiserslautern in Kaiserslautern, Germany. Matthew spent the summer of 2019 in Germany as a scholar in the German Academic Exchange Service (DAAD) Research Internships in Science...

Matthew Participates in Penn State’s Global Fellows Program

Matthew Aronson shares his experiences studying at the National University of Singapore during the spring 2018 semester. As a Global Engineering Fellow, Matthew acts as both an ambassador for the College of Engineering study abroad programs and as a peer adviser for...

Our Research

Research in the Precision Therapeutics and Bioresponsive Materials Lab, led by Dr. Scott Medina, interfaces chemical biology and nanotechnology to develop new tools that enable the analysis and precise control of cells in complex biologic microenvironments. Central to our work is understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. Mechanistic insights gained from these studies guide the design of bio-inspired functional materials around which we develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer. To learn more about our work, please click on the images below:

Image-Guided Theranostics

Precision Antimicrobials

Biomimetic Nanomaterials

The Team

 Scott Medina, Ph.D.

 Principal Investigator

 Janna Sloand, M.S.

 Graduate Student

 Andrew Simonson

 Graduate Student

 Atip Lawanprasert

 Graduate Student

 Michael Miller

 Graduate Student

Yasmin Ali

 Schreyer Honors Scholar

Sarah Almarzooqi

 Schreyer Honors Scholar

Tomer Eldor

 Schreyer Honors Scholar

Sopida Pimcharoen

 Undergraduate Researcher