The Precision Therapeutics and Bioresponsive Materials Lab

Welcome to the Medina Group at Penn State!

Working at the interface of chemical biology and nanomedicine, WE ARE developing advanced tools that can open new opportunities in precision medicine.

New Paper Accepted in Nanomedicine!

Andrew's paper on peptide-polysaccharide nanogels has been accepted for publication in Nanomedicine, titled: "Bioresponsive Peptide-Polysaccharide Nanogels - A Versatile Delivery System to Augment the Utility of Bioactive Cargo."

New Paper in Acta Biomaterialia!

Matthew and Andrew publish their co-authored work in Acta Biomaterialia, titled “Lipopeptisomes: Anticancer peptide-assembled particles for fusolytic oncotherapy“. Nice job...

Work from the Medina Group Published in Angewandte Chemie!

Our work on ultrasound sensitive template-assembled peptide nano-emulsions is published in Angewandte Chemie, titled: "Fluorous Phase-Directed Peptide Assembly Affords Nano-Peptisomes Capable of Ultrasound-Triggered Cellular Delivery."...

Our Research

Research in the Precision Therapeutics and Bioresponsive Materials Lab, led by Dr. Scott Medina, interfaces chemical biology and nanotechnology to develop new tools that enable the analysis and precise control of cells in complex biologic microenvironments. Central to our work is understanding how peptides and proteins assemble at natural and non-natural interfaces to form organized structures with unique biochemical functions. Mechanistic insights gained from these studies guide the design of bio-inspired functional materials around which we develop new biosensing and therapeutic strategies to treat infectious disease, inflammation and cancer. To learn more about our work, please click on the images below:

Image-Guided Theranostics

Precision Antimicrobials

Biomimetic Nanomaterials

The Team

 Scott Medina, Ph.D.

 Principal Investigator

 Janna Sloand, M.S.

 Graduate Student

 Andrew Simonson

 Graduate Student

 Atip Lawanprasert

 Graduate Student

Agustey Mongia

 Schreyer Honors Scholar

Matthew Aronson

 Schreyer Honors Scholar

Juan Dalo

 Schreyer Honors Scholar

Danial Nasirullah

 Undergraduate Researcher

Alda Chau

 Undergraduate Researcher
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