Publications and Presentations

Co-authored or with the support of the NMR Facility:

23.  Silverberg, L. J.; Pacheco, C.; Lagalante, A.; Tierney, J.; Bachert, J.; Bayliff, J. A.; Cali, A. S.; Chen, L.; Cooper, A. D.; Minehan, M. J.; et al. Synthesis and Spectroscopic Properties of a Series of Novel 2-Aryl-3-Phenyl-2,3-Dihydro-4H-1,3-Benzothiazin-4-Ones. ARKIVOC 2016,(vi), 122–143. DOI: http://dx.doi.org/10.3998/ark.5550190.p009.875.
22. Wilfong, W. C.; Kail, B. W.; Jones, C. W.; Pacheco, C.; Gray, M. Spectroscopic Investigation of the Mechanisms Responsible for the Superior Stability of Hybrid Class 1/Class 2 CO2 Sorbents: A New Class 4 Category. ACS Applied Materials & Interfaces 2016. Articles ASAP. DOI: 10.1021/acsami.6b02062.
21. Cai, J.; Zhang, L.; Jones, R.; Correll, J.; Hatzakis, E.; Smith, P.; Gonzalez, F.; Patterson, A. The Anti-Oxidant Drug Tempol Promotes a State of Anti-Obesity Through Functional Metabolic Changes in the Gut Microbiota. J Proteome Res 2016, 15 (2), 563.


20. Richard L. Gill Jr., Jean-Philippe Castaingb, Jen Hsinc, Irene S. Tanb,d, Xingsheng Wanga, Kerwyn Casey Huangc, Fang Tiana, and Kumaran S. Ramamurthib. Structural basis for the geometry-driven localization of a small protein, PNAS, Published online March 30, 2015.
19. Dey, K. K.; Pong, F. Y.; Breffke, J.; Pavlick, R.; Hatzakis, E.; Pacheco, C.; Sen, A. “Dynamic Coupling at the Ångström Scale” Angew. Chem. Int. Ed. 2015, 54, 1 | DOI:10.1002/anie.201509237.
18. Sariola V.; Pena-Francesch, A.; Jung, H.; Çetinkaya, M.; Pacheco, C.; Sitti, M.; Demirel, M. C. “Segmented molecular design of self-healing proteinaceous materials” Scientific Reports 2015, 5, 13482 | DOI: 10.1038/srep13482.
17. Van Buiten, C.; Pacheco, C.; Hatzakis, E.; Elias, R. “Influence of molecular structure on interactions of dietary polyphenols and an immunodominant gluten peptide”, 2015, ACS National Meeting, Boston, MA, August 16 – 20.
16. Silverberg, L. J.; Pacheco, C. N.; Lagalante, A.; Cannon, K. C.; Bachert, J. T.; Xie, Y.; Baker, L.; Bayliff, J. A. “Synthesis and Spectroscopic Properties of 2,3-Diphenyl-1,3-thiaza-4-one heterocycles” International Journal of Chemistry 2015, 7, 1150.
15. Hatzakis, E.: “Applications of NMR Spectroscopy in olive oil analysis”. PANIC NMR Conference, San Diego, CA, USA, February 2015.
14. Hatzakis, E.: “Determination of Phospholipids in Olive Oil Using Multinuclear NMR Spectroscopy”. AOCS, Session: PHO 2: Nutrition and Analytics of Phospholipids. Orlando, FL, USA, May 2015.
13. Hatzakis, E.: “Analysis of Marine Dietary Supplement Using NMR Spectroscopy”. AOCS, Session: ANA 3.1/IOP 3: Algal and Other Non-traditional Oils Characterization. Orlando, FL, USA, May 2015.
12. Hatzakis, E.: “Applications of NMR-based methods for the analysis of fish oil and olive oil”. U.S. Food and Drug Administration (FDA), Center for Food Safety and Applied Nutrition (CFSAN), College Park, MD, USA, May 2015.
11. Hatzakis, E.: “Applications of NMR Spectroscopy in Food Science, Structure Biology and Metabolomics”. REU seminar program at Penn State University, Department of Chemistry, University Park, PA, June 2015.
10. Quarles, Kaycee A.Chadalavada, Durga, Showalter, SA. “Deformability in the cleavage site of primary microRNA is not sensed by the double-stranded RNA binding domains in the microprocessor component DGCR8” PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2015, 83, 6, 1165.
9. Zhang, L.; Correll, R.; Tanaka, N.; Murray, I.; Smith, P.; Hao, R.; Albert, I.; Hatzakis, E.; Gonzalez, F.; Perdew, G.;. Patterson, A. Aryl Hydrocarbon Receptor Activation by Persistent Organic Pollutants Impacts Gut Microbiome-Host Metabolic Homeostasis. Environmental Health Perspectives, 2015, 123, 679-688. Science Selections, p. A187.
8. Dais, P.; Misiak, M.; and Hatzakis, E. Analysis of marine dietary supplement using NMR spectroscopy. Analytical Methods, 2015, 7, 5226- 5238.
7. Zhang, L.; Hatzakis, E.; Nichols, R.; Correll, J.; Smith, P.; Perdew, G.; Patterson, A. Metabolic responses of mice to dietary TCDF revealed by a combination of global and targeted analysis. Environmental Science and Technology, 2015, 49, 8067–8077.


6. Hatzakis, E.: Studying Parallel-Stranded G-Quadruplex Structures of promoter DNA using NMR Spectroscopy”. Conference on Research and Education in NMR and MS spectroscopy, Wilkes, PA, USA, May 2014.
5. Jennifer M. Axe,† Eric M. Yezdimer,† Kathleen F. O’Rourke,† Nicole E. Kerstetter,† Wanli You,‡ Chia-en A. Chang,‡ and David D. Boehr*,† Amino Acid Networks in a (β/α)8 Barrel Enzyme Change during Catalytic Turnover J. Am. Chem. Soc. 2014, 136, 6818−6821.
4. Mathé, E.; Patterson, A.; Haznadar, M.; Manna, S.; Krausz, K.; Bowman, E.; Shields, P.; Idle, J.; Smith, P.; Anami, K.; Kazandjian, D.; Hatzakis, E.; Gonzalez, F.; Harris, C. Non-invasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer. Cancer Research. 2014, 74, 3259-3270.
3. Aumiller, W.; Davis, B.; Hatzakis, E.; Keating, C. Interactions of Macromolecular Crowding Agents and Cosolutes with Small Molecule Substrates: Effect on Horseradish Peroxidase Activity with Two Different Substrates. Journal of Physical Chemistry B, 2014. 118, 10624−10632.
2. Hatzakis, E.: SMASH 2014, Atlanta, GA, USA. Poster: Compositional analysis of encapsulated fish oil supplements using multinuclear and multidimensional NMR spectroscopy.


1. Xiaorong Yang, Eric D. Smidansky, Kenneth R. Maksimchuk, David Lum,1 Jesse L. Welch,1 Jamie J. Arnold, Craig E. Cameron, and David D. Boehr. Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition Structure 20, 1519–1527, September 5, 2012.