Despite being identified more than a century ago, the knowledge surrounding schizophrenia is fairly limited. The diagnosis carries an intense stigma, with outsiders assuming that people with schizophrenia are violent and unproductive members of society. Because of this stigma, many don’t reach out to mental health care providers and suffer in silence.
The DSM-5 lists five key symptoms of psychotic disorders: 1) delusions, 2) hallucinations, 3) disorganized speech, 4) disorganized or catatonic behavior, and 5) negative symptoms. To be diagnosed with schizophrenia, the person must have at least 2 of these symptoms and 1 of the 2 must be either delusions, hallucinations, or disorganized speech. Delusions are clearly false beliefs that represent abnormalities in a person’s thoughts. Hallucinations are sensations or perceptions in the absence of an external stimulus. They can be auditory (such as hearing voices) or visual (such as seeing a ghost); though auditory hallucinations are much more common. Disorganized speech is speech abnormalities that make it difficult or impossible to comprehend. Disorganized behavior is behavior that is self-contradictory or extremely inconsistent behavior, while catatonic behavior is unresponsiveness in a person that is awake. Lastly, negative symptoms include the ability to empathize with others, apathy, and withdrawal from social situations. These symptoms are called “negative” because the person loses these abilities as their condition progresses.
Schizophrenia is a syndrome, which means that there are several different causes for the symptoms. However, as I said earlier, schizophrenia is not well understood due to the large stigma associated with the diagnosis. One cause that psychologists now believe to be associated with the condition is genetics. If an identical twin is diagnosed with schizophrenia, there is a 40% chance that the other twin will also be diagnosed. Additionally, family members of those who have schizophrenia tend to have milder versions of schizophrenic symptoms. Schizophrenia is thought to be one of the highest genetic-related mental illness. Aside from genetics, the environment also matters. There is new research coming out that associates schizophrenia with exposure to certain viruses in childhood. Additionally, those who have a high risk of schizophrenia (from genetics) may trigger the condition by using drugs.
Often, people with schizophrenia will only begin receiving treatment after their first psychotic episode, which is long after the initial onset of symptoms. Despite this delayed treatment, medication and therapy can be effective. Antipsychotics decrease levels of dopamine in the brain, which can help with many of the positive symptoms (delusions, hallucinations and disorganized speech); however, they may make negative symptoms worse. Luckily, there is lots of research happening right now to find drugs that improve positive symptoms without making negative symptoms worse.