Abstract: Alzheimer’s disease is a neurodegenerative disease associated with loss of memory and cognitive function. The aggregation of extracellular plaques containing β-amyloid is related to the processing of the amyloid precursor protein (APP). When endocytosed to...
Abstract: Oligodendrocytes are brain cells that myelinate axons to assist in the conduction of action potentials. They can communicate with other brain cells by releasing extracellular vesicles (EVs), which contain proteins, lipids, and nucleic acids, including...
Abstract: The importance of the placenta is often underrepresented, although it facilitates the transfer of oxygen and nutrients to the fetal bloodstream. Iron is a prominent nutrient responsible for general development, and inadequate levels have been shown to induce...
Abstract: The Great Lakes support a thriving viticulture industry in the northeastern United States, which drives the local economies of this region. Agricultural productivity in the Lake Erie wine belt is threatened seasonally by the grape berry moth (GBM; Endopiza...
Abstract: Cellular communication involves the transduction of signals between cells and their environment. On a fundamental level, this requires the cell to recognize and appropriately respond to specific molecular signaling. Extracellular signal-regulated kinase...
Abstract: In the yeast Saccharomyces cerevisiae, trafficking of a variety of proteins between the cell surface, trans-Golgi network (TGN), endosomes, and vacuole is regulated by clathrin adaptors. In this study, we focused on the role of the TGN-endosomal clathrin...
