Welcome to the Smoking and Health Behavior Research Laboratory at the Pennsylvania State University. The mission of our lab is to contribute to the scientific understanding of smoking behaviors including smoking onset, nicotine addiction, novel nicotine delivery systems, and smoking reduction. Our overall goal is to increase our understanding of dependence as well as prevention and cessation efforts. We are involved in a variety of laboratory-based research studies including studies on the influence of genetic expression on nicotine metabolism and withdrawal, secondary data analyses of nationally representative samples, and outcomes of the American Lung Association’s youth smoking cessation program Not On Tobacco (N-O-T). We are also dedicated to providing quality, hands-on, multidisciplinary training and education for both undergraduate and graduate students with interests in tobacco research.