Compiled from NIH R21 website by Nimisha Muttiah.
Funding Priorities for R21 grants: The R21 grant mechanism is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development. Of the R21 grants, I am specifically focusing on the “Brain Disorders in the Developing World: Research Across the Lifespan” grant.
Funding Priorities for this specific grant: This Funding Opportunity Announcement (FOA) encourages exploratory/developmental planning grant applications proposing the development of innovative, collaborative research and research training projects, between high income country (HIC) and low- to middle-income country (LMIC) scientists, on brain and other nervous system function and disorders throughout life, relevant to LMICs.
Type of Grant Funded: The R21 grant will provide support to assess needs, to initiate preliminary studies and training, and to organize, plan, prepare, and assemble the information and data for an application for a more comprehensive R01 application involving collaboration between the HIC and LMIC investigators.
Eligibility: Higher Education Institutions, nonprofits other than institutions of higher education, for profit organizations, government organizations, foreign (non-U.S.) components of U.S. organizations.
Level of Funding Provided: Up to $100,000 per year for up to two years.
Grant Application: Application
Grant Application Guides: Guide
- The project should involve at least two institutions, one in a HIC and one in a LMIC to be involved as collaborative partners in the grant application.
- The project should lead to pursuit of basic, epidemiological, clinical, prevention, intervention or health services research, in the area of nervous system development, function and impairment throughout life, of relevance to LMIC countries
- Activities undertaken under the R21 planning grant may also include, but are not limited to: training activities for the LMIC site collaborators targeted to the research area to be addressed and identification of the ways in which the basic research could be applied to clinical issues.
- Projects involving neurodevelopmental disorders and related cognitive disorders (such as mental retardation, behavioral disorders, learning disabilities and cerebral palsy) that result from abnormal prenatal development or influences during the prenatal and perinatal period, or from injury or insult to the brain and central nervous system during infancy or childhood will be considered.
- Letter of Intent: January 14th, 2013
- Application: February 14th, 2013
Category: National Institute of Health (NIH)
Examples of Funded Grants:
1) Chemokines in Zambian children with Cerebral Malaria (PI: Monique F. Stins, Johns Hopkins University).
• This is an initial R21 research and capacity building proposal intending to set the basis for an extended future collaboration that will focus on the role of chemokines in CM-mediated neurological dysfunction, how this affects a patient’s life and development, and how the neurologic sequelae can be prevented in the future.
• The purpose of this project is to broaden the existing prodrome to psychosis study to populations in a different cultural and genetic pool to examine the important cultural differences in the manifestations of the symptoms and the predictors of the illness. The overall goal of this application is to design and initiate a sustainable clinical high-risk phase to psychosis longitudinal program of research in a low-middle Income country.