Tom Spratt is program chair for the Division of Chemical Toxicology of the American Chemical Society for 2017 and 2018.
The tentative program for the meeting in Washington DC on August 20-24, 2017 is
- Chemical Research in Toxicology, Young Investigators Symposium
- To be determined by Chemical Research in Toxicology
- Founders’ Award Symposium
- Ian Blair, Founders’ Award Winner, , University of Pennsylvania
- Larry Marnett, Vanderbilt University
- F. Peter Guengerich, Vanderbilt University
- Trevor Penning, University of Pennsylvania
- Steve Tannenbaum, MIT
- General Oral Papers
- to be determined from submitted abstracts
- Young Investigators Symposium
- to be determined from submitted abstracts
- Biological Targets of Botanical Supplements. Organizer Judy Bolton
- Richard van Breemen, University of Illinois, at Chicago, Pharmacokinetic Interactions between Drugs and Licorice Botanical Dietary Supplements Used by Menopausal Women
- Mary F. Paine, Washington State University, Intestinal UGTs as targets for pharmacokinetic natural product-drug interactions
- Tom Kensler, Johns Hopkins. KEAP1 and done? Targeting the NRF2 pathway with sulforaphane
- Cynthia Rider, NIEHS, Biological Endpoints versus Chemistry in Determining Sufficient Similarity of Botanical Dietary Supplements
- Judy Bolton, University of Illinois, at Chicago, Botanicals modulate estrogen metabolism through multiple targets
- Toxicological Considerations in Antibody Drug Conjugate Design and Development, Organizers, Fred Guengerich, Nick Meanwell and Griff Humphries
- Pamela A. Trail, Regeneron, Overview of the area and challenges
- Christopher J. O’Donnell, Pfizer, Optimization of Tubulysin Antibody-Drug Conjugates: A Case Study in Addressing ADC Metabolism
- S. Cyrus Khojasteh , Genentech, Linker Immolation and Cell Killing Activity
- Peter Senter, Seattle Genetics, ADME Considerations for the Development of Antibody-Drug Conjugates
- Sanjeev Gangwar, Bristol-Myers Squibb, Expanding the Reach of Antibody-Drug Conjugates
- Crosslink DNA repair. Organizers, Yinsheng Wang and Orlando Scharer
- Johannes Walter, Harvard Medical School, A new mechanism of replication-coupled ICL repair
- Kent Gates, Uniersity of Missouri, Interstrand cross-links derived from abasic sites in duplex DNA
- Lei Li , MD Anderson, Fanconi Anemia pathway and Constitutive Protection of Replication Stress
- Xiaohua Peng, University of Wisconsin, Milwaukee, Hydrogen Peroxide Activated DNA Cross-Linking Agents and Their Biomedical Application
- Michael Seidman,NIH/NIA, Baltimore, Lesion proximal FANCD2 participates in replication independent repair of DNA interstrand crosslinks
- Yinsheng Wang, University of California, Riverside, Occurrence, Repair and Biological Consequences of Psoralen- and Abasic Site-derived Interstrand Crosslink Lesions
- Mass Spectrometry applications in RNA toxicology. Organizer Silvia Balboa, Peter Villalta
- Hans Maurer, Saarland University, Overview on newly developed mass spectrometry methodologies and approaches in toxicology
- Limbach Patrick, Department of Chemistry, University of Cincinnati, Chemical modification of RNA for function analysis
- Benedikt Warth, University of Vienna, Novel approaches in targeted metabolomics for the investigation of food toxicants
- Claire Russell, Kings College London, New approach for tissue and fluid proteomics with Tandem Mass Tags to identify low abundant protein biomarkers of disease
- Silvia Balbo, University of Minnesota, Characterization of DNA damage and the investigation of genotoxicity