Bioengineering
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Developing biomaterials and bioengineering techniques for creating scaffolds and artificial tissues.
Physiological Responses to Biomaterials
The interaction of human tissues with biomaterials can cause a variaty of physiological responses. Dr. Christopher Siedlecki lab studies the response of blood system to synthetic materials upon implantation, interactions of proteins with biomaterial surfaces, the development of novel strategies for synthesis and modification of biomaterials including nanotechnology, mechanisms of thrombogenesis, formation of surface-induced thrombus on implanted cardiovascular devices. To visit Dr. Siedlecki profile, click here.
Musculoskeletal Regenerative Engineering
Surface based control of cellular functions can have a significant impact on biomaterial based regenerative therapies. The Musculoskeletal Regenerative Engineering lab leaded by Dr. Justin Brown studies the fundamental mechanisms by which biomaterial interfaces to alter the proliferation, migration and differentiation of mesenchymal stem cells to guide the design of biomaterial scaffolds and facilitate the generation or regeneration of musculoskeletal tissues. To learn more, visit Dr. Brown’ s profile.
3D Printing
3D printing is a manufacturing technique that creates three-dimensional objects by building successive layers of raw material such as metals, plastics, and ceramics. It attracts a considerable attention in the health care and bioengineering fields because of its potential to improve treatment for certain medical conditions. Dr. Ibrahim Ozbolat lab focuses on establishing cutting-edge bioprinting science and technology for engineering around 10 different tissue types. To learn more, visit Dr. Ozbolat research profile, book, and laboratory website.
Transformative Biomaterials and Biotechnology
The methodology for functional biomaterial development and the use of biomaterials as a tool to solve unmet clinical problems are investigated in the Transformative Biomaterials and Biotechnology Lab (TBBL) lead by Dr. Jian Yang. Dr. Yang and his team work on solving complex bioengineering problems such as (i) methodology for new biomaterial development; (ii) soft and hard tissue engineering; (iii) cancer drug delivery and imaging; (iv) stem cell/biomaterial interactions; (v) micro-/nano-medical device fabrication; (vi) biosensing. To learn more, visit Dr. Yang’s profile.
Tendon Regeneration
Degenerative processes are a common outcome of tendon and ligament injuries leading to disabilities. The research in Dr. Spencer Szczesny’s laboratory investigates the interplay between tendon multiscale mechanics and mechanobiology in the context of tissue remodeling. This multidisciplinary work involves the use of multiscale mechanical testing, computational modeling, cell and tissue culture, and biomaterial fabrication. To learn more, visit Dr. Szczesny’s research profile.
Drug Delivery, Tissue Engineering, and Regenerative Medicine
The development of optically and magnetically modulated drug delivery systems, quasi 3D cell sheet culture systems, and hybrid in situ polymerizing grafts/augments are among research directions of Dr. Daniel Hayes’ lab. To read about Dr. Hayes’ lab experimmental work with injectable in situ polymerizing bone grafts “bone foam”, the hybrid semisynthetic ECM gels, and the quasi 3-D tissue culture-cell sheets, visit Hayes’ Lab and research profile.