Hematopoietic Stem Cells

By Lilly Su, MD Candidate, Class of 2023, Penn State College of Medicine Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells, through a process called hematopoiesis. There are many organs and tissues within the body that are involved...

Why Stem Cells?

By Lilly Su, MD Candidate, Class of 2023, Penn State College of Medicine Within the body, the majority of cells are destined to convey specific functions e.g., erythroid blood cells deliver oxygen, endothelial cells form vasculature, neurons mediate communication by...

From pluripotency to blood.

Hematopoietic differentiation of pluripotent stem cells in vitro Pluripotent stem cells (PSCs) derived from the inner part of a blastocyst (embryonic stem cells, ESCs) or through reprogramming of terminally differentiated adult cells (induced pluripotent stem cells,...

The history of Next Generation Sequencing (NGS).

Since the deoxyribonucleic acid (DNA) was discovered by Oswald Avery in 1944 and its double helical strand structure composed of four bases was determined by Watson and Crick in 1953, our knowledge about genome structure and function has tremendously increased. This...