Publications
Temporal radiographic and histological study of necrosis development in a mouse glioblastoma model.
Patricia P. Yee, Jianli Wang, Stephen Y. Chih, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Krishnamoorthy Thamburaj, Wei Li. 2022. Front. Oncol. doi: 10.3389/fonc.2022.993649. Link to Pubmed
Calcium, an Emerging Intracellular Messenger for the Hippo Pathway Regulation
Yiju Wei and Wei Li. 2021. Front. Cell Dev. Biol. doi: 10.3389/fcell.2021.694828. Link to Pubmed
Tumor necrosis: A synergistic consequence of metabolic stress and inflammation.
Patricia P. Yee, Wei Li. 2021. Bioessays. doi: 10.1002/bies.202100029. Link to Pubmed
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression.
Patricia P. Yee, Yiju Wei, Soo-Yeon Kim, Tong Lu, Stephen Y. Chih, Cynthia Lawson, Miaolu Tang, Zhijun Liu, Benjamin Anderson, Krishnamoorthy Thamburaj, Megan M. Young, Dawit G. Aregawi, Michael J. Glantz, Brad E. Zacharia, Charles S. Specht, Hong-Gang Wang, Wei Li. 2020. Nature Communications. doi: 10.1038/s41467-020-19193-y. Link to Pubmed
NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.
Yiju Wei , Patricia P Yee , Zhijun Liu , Lei Zhang, Hui Guo, Haiyan Zheng, Benjamin Anderson, Melissa Gulley, Wei Li. 2020. EMBO Reports. doi: 10.15252/embr.202050642. Link to Pubmed
L-type Ca2+ channel blockers promote vascular remodeling through activation of STIM proteins.
Martin T Johnson, Aparna Gudlur, Xuexin Zhang, Ping Xin, Scott M Emrich, Ryan E Yoast, Raphael Courjaret, Robert M Nwokonko, Wei Li, Nadine Hempel, Khaled Machaca, Donald L Gill, Patrick G Hogan, Mohamed Trebak. 2020. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.2007598117. Link to Pubmed
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.
Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, Sebastian Brabetz, Laura Sieber, Melissa Gulley, Monika Mauermann, Tatjana Wedig, Norman Mack, Yuka Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, Felipe Andreiuolo, Eric Holland, Kendra Maass, Huiqin Körkel-Qu, Hai-Kun Liu, Felix Sahm, David Capper, Jens Bunt, Linda J. Richards, David T. W. Jones, Andrey Korshunov, Lukas Chavez, Peter Lichter, Mikio Hoshino, Stefan M. Pfister, Marcel Kool, Wei Li & Daisuke Kawauchi. 2019. Nature Communications. doi: 10.1038/s41467-019-11884-5. Link to Pubmed
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis.
, , , , , Wei Li. 2019. Journal of Cell Science,doi: 10.1242/jcs.225714. Link to Pubmed
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells.
Lei Zhang, Fangling Cheng, Yiju Wei, Lijun Zhang, Dongsheng Guo, Baofeng Wang, Wei Li. 2018. Oncogene, doi.org/10.1038/s41388-018-0626-0. Link to Pubmed
Induction of store operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ.
Liu Z., Wei Y., Zhang L., Yee P.P., Johnson M., Zhang X., Gulley M., Atkinson J.M., Trebak M., Wang H.G., Li W. 2018. Oncogene, doi.org/10.1038/s41388-018-0425-7. Link to Pubmed
2016 Children’s Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis
Fisher, M. J. , Belzberg, A. J. , de Blank, P. , De Raedt, T. , Elefteriou, F. , Ferner, R. E. , Giovannini, M. , Harris, G. J. , Kalamarides, M. , Karajannis, M. A. , Kim, A. R. , Lázaro, C. , Le, L. Q. , Li, W. , Listernick, R. , Martin, S. , Morrison, H. , Pasmant, E. , Ratner, N. , Schorry, E., May 1 2018. American Journal of Medical Genetics, Part A. 176, 5, p. 1258-1269. Link to Pubmed
Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
Chen, Y. B. , Xu, J. , Skanderup, A. J. , Dong, Y. , Brannon, A. R. , Wang, L. , Won, H. H. , Wang, P. I. , Nanjangud, G. J. , Jungbluth, A. A. , Li, W. , Ojeda, V. , Hakimi, A. A. , Voss, M. H. , Schultz, N. , Motzer, R. J. , Russo, P. , Cheng, E. H. , Giancotti, F. G. , Lee, W. , Oct 7 2016. Nature communications. 7, 13131. Link to Pubmed
Apoptotic mechanisms during competition of ribosomal protein mutant cells: Roles of the initiator caspases Dronc and Dream/Strica
Kale, A., Li, W., Lee, C. H. & Baker, N. E. Aug 7 2015. Cell Death and Differentiation. 22, 8, p. 1300-1312. Link to Pubmed
Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DCAF1-Mediated Inhibition of the Hippo Pathway Kinases Lats1 and 2 in the Nucleus
Li, W., Cooper, J., Zhou, L., Yang, C., Erdjument-Bromage, H., Zagzag, D., Snuderl, M., Ladanyi, M., Hanemann, C. O., Zhou, P., Karajannis, M. A. & Giancotti, F. G. Jul 14 2014. Cancer Cell. 26, 1, p. 48-60. Link to Pubmed
Merlin: A tumour suppressor with functions at the cell cortex and in the nucleus
Li, W., Cooper, J., Karajannis, M. A. & Giancotti, F. G. 2012. EMBO Reports. 13, 3, p. 204-215. Link to Pubmed
Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4 DCAF1 to suppress oncogenic gene expression
Cooper, J., Li, W., You, L., Schiavon, G., Pepe-Caprio, A., Zhou, L., Ishii, R., Giovannini, M., Hanemann, C. O., Long, S. B., Erdjument-Bromage, H., Zhou, P., Tempst, P. & Giancotti, F. G. Aug 30 2011. Science Signaling. 4, 188. Link to Pubmed
Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus
Li, W., You, L., Cooper, J., Schiavon, G., Pepe-Caprio, A., Zhou, L., Ishii, R., Giovannini, M., Hanemann, C. O., Long, S. B., Erdjument-Bromage, H., Zhou, P., Tempst, P. & Giancotti, F. G. Feb 19 2010. Cell. 140, 4, p. 477-490. Link to Pubmed
Merlin’s tumor suppression linked to inhibition of the E3 ubiquitin ligase CRL4DCAF1
Li, W. & Giancotti, F. G. Nov 15 2010. Cell Cycle. 9, 22, p. 4433-4436. Link to Pubmed
Oriented Cell Division as a Response to Cell Death and Cell Competition
Li, W., Kale, A. & Baker, N. E. Nov 17 2009. Current Biology. 19, 21, p. 1821-1826. Link to Pubmed
Cell competition and its possible relation to cancer
Baker, N. E. & Li, W. Jul 15 2008. Cancer Research. 68, 14, p. 5505-5507. Link to Pubmed
Engulfment Is Required for Cell Competition
Li, W. & Baker, N. E. Jun 15 2007. Cell. 129, 6, p. 1215-1225. Link to Pubmed
Genes affecting cell competition in drosophila
Tyler, D. M., Li, W., Zhuo, N., Pellock, B. & Baker, N. E. Feb 2007. Genetics. 175, 2, p. 643-657. Link to Pubmed
The active role of corpse engulfment pathways during cell competition
Li, W. & Baker, N. E. 2007 Fly. 1, 5, p. 274-278. Link to Pubmed
Analyses of RAS Regulation of Eye Development in Drosophila melanogaster
Firth, L. C., Li, W., Zhang, H. & Baker, N. E. Dec 1 2005. Methods in enzymology. 407, p. 711-721. Link to Pubmed