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 The Yengo Lab Investigates Molecular Motor and Cytoskeletal Proteins

 

• The structural mechanism of force generation in myosin.
• Genetic mutations in myosin associated with heart failure, deafness, and other diseases.
• Physiological mechanisms of contractile dysfunction in skeletal and cardiac muscle.

 

 

 

 

 

The edge of a COS-7 cell expressing GFP-tagged MYO3A and stained with Alexa555 phalloidin to visualize the actin.

                                                                                                                     Cardiomyocytes stained with Alexa488 phalloidin to                                                                                                                               visualize the actin and DAPI to visualize the nucleus.

 

 

 

 

 

Check out the Physiology Department here at PSCOM!