Publications as a Principal Investigator
‡ Represents undergraduate students
69. Lux, D.; Lee, D.; Sapkota, R.; Giri, R. Iron-Mediated Dialkylation of Alkenylarenes with Benzyl Bromides. J. Org. Chem. 2024, accepted. Link
68. Singh, H.; Tak, R. K.; Poudel, D.; Giri, R. Catalytic Photoredox Carbobromination of Unactivated Alkenes with a-Bromocarbonyls via Mechanistically Distinct Radical-Addition Radical-Pairing Pathway. ACS Catal. 2024, Accepted. Link
Available on Preprint. Link
67. Lakomy, M. G.; Del Rio, A. C.; Giri, R. Ni-Catalyzed Linearizable Cyclization/Alkylmetal Interception with Silicon-Oxygen as a Detachable Linker: Regioselective Access to 1,2-Oxasilolane Heterocycles, 3-Hydroxysilanes and 4-Arylalkanols, Angew. Chem. Int. Ed. 2024, accepted. Link
Available on Preprint. Link
66. Poudel, D. P.; Pokhrel, A.†; Tak, R. K.†; Shankar, M; and Giri, R.* Photosensitized Dioxygen Enables Intermolecular Cyclopropanation of Alkenes Directly with Active Methylene Compounds, Science 2023, 381, 545-553. Link
Available on Preprint. Link
Featured on Synform 2024/01, A3–A5. Link
C&EN News. Link
Italy24 News. Link 
Sohu News (China). Link 
N+1 News (Russia). Link 
ScienceDaily News. Link 
Technology Networks News. Link 
TECHEXPLORIST News. Link 
PSU Press Release. Link 
Eberly College of Science News Release. Link 
65. Katzbaer, J.; Torres, V.; Elacqua, E.; Giri, R. Nickel-Catalyzed Alkene Difunctionalization as a Method for Polymerization. J. Am. Chem. Soc. 2023, Accepted. Link
Highlighted by Synfacts 2023; 19(10): 0978. Link
64. Lux, D. M.; Aryal, V.; Niroula, D.; Giri, R. Ni-Catalyzed Regioselective Intermolecular Dialkylation of Alkenylarenes: Generation of Two Vicinal C(sp3)-C(sp3) Bonds Across Alkenes. Angew. Chem. Int. Ed. 2023, Accepted. Link
Available on Preprint. Link
Highlighted by Synfacts 2023; 19(10): 0990. Link
63. Chesley, L. J.; Poudel, D. P.; Sapkota, R. R.; Dhungana, R. K.; Lakomy, M. G.; Giri, R. Pd-Catalysed 1,3-Alkenylarylation of Skipped Diene via Metal Migration, ACS Omega 2023, accepted. Link
62. Wickham, L. M.; Dhungana, R. K.; Giri, R. Ni-Catalyzed Regioselective Reductive 1,3-Dialkenylation of Alkenes. ACS Omega 2023, 8, 1060-1066. Link
61. Aryal, V.; Chesley, L.; Niroula, D.; Sapkota, R.; Dhungana, R.; Giri, R. Ni-Catalyzed Regio- and Stereoselective Alkylarylation of Unactivated Alkenes in γ,δ-Alkenylketimines. ACS Catal. 2022, just accepted. Link
60. Sapkota, R. R.; Tak, R. K.; Aryal, V.; Niroula, D.; Secosky, N. C.; Dhungana, R. K.; Giri, R. “Cu-Catalyzed Cyclization/Coupling of Alkenyl Aldimines with Arylzinc Reagents. Access to Indole-3-diarylmethanes” Org. Lett. 2022, Just Accepted. Link
Preprint, ChemRxiv 2022, DOI: 10.26434/chemrxiv-2022-d6qn6. Link
59. Dhungana, R. K.†; Sapkota, R. R.†; Wickham, L. M.; Niroula, D.; Shrestha, B.; Giri, R. “Ni-Catalyzed Arylbenzylation of Alkenylarenes. Kinetic Studies Reveal Autocatalysis by ZnX2” Angew. Chem. Int. Ed. 2021, Just Accepted. Link
Preprint, ChemRxiv 2021, DOI: 10.33774/chemrxiv-2021-0nw8q. Link
58. Wickham, L.; Giri, R. “Transition Metal (Ni, Cu, Pd)-Catalyzed Alkene Dicarbofunctionalization Reactions” Acc. Chem. Res. 2021, Accepted. Link
57. Dhungana, R. K.; Aryal, V.; Niroula, D.; Sapkota, R. R.; Lakomy, M. G.; Giri, R. “Ni-Catalyzed Regioselective Alkenylarylation of γ,δ-Alkenyl Ketones via Carbonyl Coordination” Angew. Chem. Int. Ed. 2021, Just Accepted. Link
56. Dhungana, R. K.; Sapkota, R. R.; Wickham, L. M.; Niroula, D.; Giri, R. “Ni-Catalyzed Regioselective 1,2-Dialkylation of Alkenes Enabled by the Formation of Two C(sp3)-C(sp3) Bonds” J. Am. Chem. Soc. 2020. Just Accepted. Link
Most read article in JACS in December 2020!
55. Dhungana, R. K.; Sapkota, R. R.; Niroula, D.; Giri, R. “Walking Metals: Catalytic Difunctionalization of Alkenes at Nonclassical Sites” Chem. Sci. 2020, Just Accepted. Link
54. Pike, R. A. S.; Sapkota, R. R.; Shrestha, B.; Dhungana, R. K.; KC, S.; Dickie, D. A.; Giri, R. “K2CO3-Catalyzed Synthesis of 2,5-Dialkyl-4,6,7-tricyano-Decorated Indoles via Carbon–Carbon Bond Cleavage” Org. Lett. 2020, Just Accepted. Link.
Highlighted by Synfacts 2020, 16(08), 0895. Link
53. KC, S.; Dhungana, R. K.; Khanal, N.; Giri, R. “Nickel-Catalyzed α-Carbonylalkylarylation of Vinylarenes. Expedient Access to γ,γ-Diarylcarbonyl and Aryltetralone Derivatives” Angew. Chem. Int. Ed. 2020, Just Accepted. Link
52. Niroula, D.†; Sapkota, R.†; Dhungana, R. K.; Shrestha,B.; Giri, R. “An Expedient Route to 9-Arylmethylanthracene Derivatives via Tandem Ni-Catalyzed Alkene Dicarbofunctionalization and Acid-Promoted Cyclization-Aromatization” Isr. J. Chem. 2020, Just Accepted. († denotes equal contribution). Link
51. Dhungana, R. K.; KC, S.; Basnet, P.; Aryal, V.; Chesley, L. J.; Giri, R. “Ni(I)-Catalyzed b,d-Vinylarylation of g,d-Alkenyl a-Cyanocarboxylic Esters via Contraction of Transient Nickellacycles” ACS Catal. 2019, Just Accepted. Link
50. KC, S.; Dhungana, R. K.; Aryal, V.; Giri, R. “Concise Synthesis of a Potential 5-Lipoxygenase Activating (FLAP) Inhibitor and its Analogs Through Late-Stage Dicarbofunctionalization” Org. Process Res. Dev. 2019, Just Accepted. Link
49. Thapa, S.; Dhungana, R. K.; Dickie, D. A.; Giri, R. “Isolation and Characterization of (Ar)(F)B(OR)2Cs and (PN)CuAr Complexes. Involvement of Cationic Copper (I) Species during transmetalation of arylboron reagents with (PN)CuF”. Tetrahedron. 2019, Just Accepted. Link
48. Basnet, P.; KC, S.; Dhungana, R. K.; Shrestha, B.; Boyle, T. J.; Giri, R. “Synergistic Bimetallic Ni/Ag and Ni/Cu Catalysis for Regioselective g,d-Diarylation of Alkenyl Ketimines: Addressing b-H Elimination by in situ Generation of Cationic Ni(II)-Catalysts” J. Am. Chem. Soc. 2018, Just Accepted. Link
47. KC, S.; Dhungana, R.; Shrestha, B.; Thapa, S.; Khanal, N.; Basnet, P.; Lebrun, R.; Giri, R. “Ni-Catalyzed Regioselective Alkylarylation of Vinylarenes via C(sp3)-C(sp3)/C(sp3)-C(sp2) Bond Formation and Mechanistic Studies” J. Am. Chem. Soc. 2018, Just Accepted. Link
46. Gokhale, R.; Thapa, S.; Artyushkova, K.; Giri, R.; Atanassov, P. “Fully Synthetic Approach towards Transition Metal-Nitrogen-Oxygen Reduction Electrocatalysts” ACS Appl. Energ. Mater. 2018, ASAP. Link
45. Basnet, P.; Dhungana, R. K.; Thapa, S.; Shrestha, B.; KC, S.; Sears, J. M.; Giri, R. “Ni-Catalyzed Regioselective b,d-diarylation of Unactivated Olefins in Ketimines via Ligand-Enabled Contraction of Transient Nickellacycles: Rapid Access to Remotely Diarylated Ketones” J. Am. Chem. Soc.2018, Just Accepted. Link
Highlighted by Synfacts 2018, 14(09), 0964. Link
44. Giri, R.; KC, S. “Strategies toward Dicarbofunctionalization of Unactivated Olefins by Combined Heck Carbometalation and Cross-Coupling” J. Org. Chem. (Synopsis) 2018, accepted. Link (Review Article)
43. Dhungana, R. K.; KC, S.; Basnet, ,P.; Giri, R. “Transition Metal-Catalyzed Dicarbofunctionalization of Unactivated Olefins” Chem. Rec. 2018, accepted. Link (Review Article)
Top Downloaded Paper 2018-2019 in Wiley!
42. KC, S.; Basnet, ,P.; Thapa, S.; Shrestha, B.; Giri, R. “Ni-Catalyzed Regioselective Dicarbofunctionalization of Unactivated Olefins by Tandem Cyclization/Cross-Coupling and Application to the Concise Synthesis of Lignan Natural Products” J. Org. Chem. 2018, accepted. Link
Highlighted by Synfacts 2018, 14(5), 0527. Link
41. Thapa, S.; Dhungana, R. K.; Thapa-Magar, R.; Shrestha, B.; KC, S.; Giri, R. “Ni-Catalyzed Regioselective 1,2-Diarylation of Unactivated Olefins by Stabilising Heck Intermediates as Pyridylsilyl-Coordinated Transient Metallacycles” Chem. Sci. 2018,9, 904-909. Link
Highlighted by Synfacts 2018, 14(4), 0180. Link
40. Shrestha, B.; Basnet, P.; Dhungana, R. K.; KC, S.; Thapa, S.; Sears, J. M.; Giri, R. “Ni-Catalyzed Regioselective 1,2-Dicarbofunctionalization of Olefins by Intercepting Heck Intermediates as Imine-Stabilized Transient Metallacycles” J. Am. Chem. Soc. 2017, 139, 10653–10656. Link
39. Thapa, S.; Basnet, P.; Giri, R. “Copper-Catalyzed Dicarbofunctionalization of Unactivated Olefins by Tandem Cyclization/Cross-Coupling” J. Am. Chem. Soc. 2017,139, 5700-5703. Link
38. Dhungana, R. K.; Shrestha, B.; Thapa-Magar, R.; Basnet, P.; Giri, R. “Pd-Catalyzed Regioselective 1,2-Dicarbofunctionalization of Unactivated Olefins by a Heck Reaction/Enolate Cyclization Cascade” Org. Lett.2017, 19, 2154-2157.Link
37. Basnet, P.; Thapa, S.; Dickie, D. A.; Giri, R. “Copper-Catalysed Suzuki-Miyaura Coupling of Alkylboron Reagents: Disproportionation of Anionic (Alkyl)(Alkoxy)borates to Anionic Dialkylborates Prior to Transmetalation” Chem. Commun.2016, 52, 11072-11075.Link
36. Shrestha, B.; Thapa, S.; Gurung, S. K.; Pike, R. A. S.‡; Giri, R. “General Copper-Catalyzed Coupling of Alkyl-, Aryl- and Alkynylaluminum Reagents with Organohalides” J. Org. Chem.2016, 81, 787-802. Link
Highlighted by Synfacts 2016, 14(4), 0403.Link
35. Thapa, S.; Vangala, A. S.‡; Giri, R. “Copper-Catalyzed Negishi Coupling of Diarylzinc Reagents with Aryl Iodides” Synthesis2016, 48, 504-511. Link (Featured Article)
34. Shrestha, B.; Giri, R. “Copper-Catalyzed Arylation of Alkyl Halides with Arylaluminum Reagents” Beilstein J. Org. Chem.2015, 11, 2400-2407. Link
33. Thapa, S.; Kafle, A.; Gurung, S. K.; Montoya, A.‡; Riedel, P.‡; Giri, R. “Ligand-Free Copper-Catalyzed Negishi Coupling of Alkyl-, Aryl- and Alkynylzinc Reagents with Heteroaryl Iodides” Angew. Chem. Int. Ed.2015, 54, 8236-8240.Link
Highlighted by Synfacts 2015; 11(8): 0853. Link
32. Thapa, S.; Shrestha, B.; Gurung, S. K.; Giri, R. “Copper-Catalysed Cross-Coupling: An Untapped Potential” Org. Biomol. Chem. 2015, 13, 4816-4827. Link
31. Gurung, S.; Thapa, S.; Shrestha, B.; Giri, R. “Copper-Catalysed Cross-Couplings of Arylboronate Esters with Aryl and Heteroaryl Iodides and Bromides” Org. Chem. Front. 2015, 2, 649-653. Link
Highlighted by Organic Process Research & Development.
Org. Process Res. Dev.2015, 19, 950−956. Link
30. Thapa, S.; Basnet, P.; Gurung, S. K.; Giri, R. “Copper-Catalysed Cross-Coupling of Arylzirconium Reagents with Aryl and Heteroaryl Iodides” Chem. Commun.2015, 51, 4009-4012. Link
Highlighted by Synfacts 2015, 11(5), 0533. Link
29. Giri, R.; Thapa, S. “Copper-Catalyzed Cross-Couplings of Organometallic Reagents with and without Assistance from PN Ligands” Synlett2015, 26, 709-715. (Synpacts) Link
Featured on theCover Page. Link
28. Thapa, S.; Gurung, S. K.; Giri, R. “2-(Diphenylphosphino)aniline” Electronic Encyclopedia of the Reagents for Organic Synthesis (eEROS), 2015.Link
27. Thapa, S.; Gurung, S. K.; Dickie, D. A.; Giri, R. “Copper-Catalyzed Coupling of Triaryl- and Trialkylindium Reagents with Aryl Iodides and Bromides via Consecutive Transmetalations” Angew. Chem. Int. Ed.2014, 53, 11620-11624. Link
Highlighted by Synfacts 2015; 11(1): 0084.Link
26. Gurung, S. K.; Thapa, S.; Shrestha, B.; Giri, R. “Copper-Catalyzed Cross-Couplings of Aryl- and Heteroaryltri-ethoxysilanes with Aryl and Heteroaryl Iodides and Bromides” Synthesis2014, 46, 1933-1937. Link
25. Giri, R.; Thapa, S.; Kafle, A. “Pd-Catalysed, Directed C-H Coupling with Organometallics” Adv. Syn. Catal.2014, 356, 1395-1411. Link
24. Gurung, S. K.; Thapa, S.; Kafle, A.; Dickie, D. A.; Giri, R. “Copper-Catalyzed Suzuki-Miyaura Coupling of Arylboronate Esters: Transmetalation with (PN)CuF and Identification of Intermediates” Org. Lett.2014, 16, 1264–1267. Link
23. Gurung, S. K.; Thapa, S.; Vangala, A. S.‡; Giri, R. “Copper-Catalyzed Hiyama Coupling of (Hetero)aryltriethoxy-silanes with (Hetero)aryl Iodides” Org. Lett.2013, 15, 5378-5381. Link
Publications as a Graduate Student and Postdoc
22. Giri, R.; Brusoe, A.; Troshin, K.; Wang, J, Y.; Font, M.; Hartwig, J. F. “Mechanism of the Ullmann Biaryl Ether Synthesis Catalyzed by Complexes of Anionic Ligands: Evidence for the Reaction of Iodoarenes with Ligated Anionic CuI Intermediates” J. Am. Chem. Soc.2018, 140, 793–806. Link
21. Gong, W.; Zhang, G.; Liu, T.; Giri, R.; Yu, J.-Q. “Site-selective C(sp3)–H Functionalization of Di-, Tri- and Tetrapeptides at the N-Terminus” J. Am. Chem. Soc.2014, 136, 16940–16946. Link
20. Giri, R.; Lan, Yu.; Liu, P.; Houk, K. N.; Yu, J.-Q. “Understanding Reactivity and Stereoselectivity in Palladium-Catalyzed Diastereoselective sp3 C-H Bond Activation: Intermediate Characterization and Computational Studies” J. Am. Chem. Soc.2012, 134, 14118. Link
19. Giri, R.; Hartwig, J. F. “Cu(I) Amido Complexes in the Ullmann Reaction. Reactions of Cu(I)-Amido Complexes with Iodoarenes with and without Autocatalysis by CuI” J. Am. Chem. Soc.2010, 132, 15860. Link
18. Tye, J. W.; Weng, Z.; Giri, R.; Hartwig, J. F. “Copper(I) Phenoxide Complexes in the Etherification of Aryl Halides” Angew. Chem., Int. Ed.2010, 49, 2185. Link
17. Giri, R.; Lam, J. K.; Yu, J.-Q. “Synthetic Applications of Pd(II)-Catalyzed C-H Carboxylation and Mechanistic Insights: Expedient Routes to Anthranilic Acids, Oxazolinones, and Quinazolinones” J. Am. Chem. Soc.2010, 132, 686. Link
16. Giri, R.; Shi, B.-F.; Engle, K. M.; Maugel, N.; Yu, J.-Q. “Transition Metal-Catalyzed C-H Activation Reactions: Diastereoselectivity and Enantioselectivity” Chem. Soc. Rev.2009, 38, 3242. Link
15. Chen, X.; Dobereiner, G.; Hao, X.-S.; Giri, R.; Maugel, N.; Yu, J.-Q. “Cu(II)-Mediated Oxidative Dimerization of 2-Phenylpyridine Derivatives” Tetrahedron2009, 65, 3085. Link
14. Giri, R.; Yu, J.-Q. “Synthesis of 1,2-and 1,3-Dicarboxylic Acids via Pd(II)-Catalyzed Carboxylation of Aryl and Vinyl C-H Bonds” J. Am. Chem. Soc.2008, 130, 14082. Link
13. Giri, R.; Maugel, N.; Foxman, B. M.;