STUDENT: Jennifer Robinson
![poster image](https://sites.psu.edu/ugrwebshowcase2022/files/2022/03/HPP-26-Jcr5673-Extracorporeal-mem_Jennifer-Robinson.png)
ADVISOR: Khalid Almasloukh
ABSTRACT:
keywords: Extracorporeal membrane oxygenation, ECMO, infants, respiratory failure, intubation, venovenous
Considering there are many infants with respiratory failure that require artificial ventilation, it is important to evaluate all options for the infant and chose the most effective method. The intervention being examined in this paper is extracorporeal membrane oxygenation (ECMO) versus other modes of artificial ventilation in infants, premature to 12 months, with respiratory failure. ECMO “is a modified form of heart-lung bypass”, meaning it can do the work of both the heart and the lungs (Smith, 2021, What is Extracorporeal Membrane Oxygenation (ECMO) section, para 3). The placement of the cannulas, or small tubes, in the infant determines if ECMO will perform as both the heart and the lungs or just the lungs. A veno-arterial (VA) ECMO is used to maintain blood flow to the organs and tissues for the heart, as well as perform the gas exchange abilities of the lungs (Esper, 2017, Types of extracorporeal membrane oxygenation circuits section, para 1). In this paper VA ECMO is not going to evaluated, rather veno-venous (VV) ECMO will be examined for its effectiveness in ventilation in infants. With VV ECMO, deoxygenated blood is removed from a large vein, has carbon dioxide removed and becomes oxygenated in the ECMO machine, and then the blood is returned to the body (Esper, 2017, Fig 1). VV ECMO is used for only respiratory issues and functions as artificial lungs. This paper will compare the effectiveness of VV ECMO in comparison to other artificial ventilation strategies, such as bedside mechanical ventilators, in infants needing artificial ventilation due to respiratory failure. After placement of the ECMO, the infant will be monitored to determine when the infant can safely be weaned off the machine. Once the infants lungs are able to function on their own, the machine will be removed (Smith, 2021, What to Expect While Your Child is on ECMO section, para 4). The length of time infants is on ECMO vary “depending on each child’s condition” (Smith, 2021, What to Expect While Your Child is on ECMO section, para 4). This paper will help to determine if ECMO is an effective form of ventilation for infants with respiratory failure in need of artificial ventilation. Research from the past ten years will be evaluated to determine the effectiveness of ECMO in comparison to other forms of artificial ventilation in infants.