Studies have found that loneliness may be a threat for health, and can even increase a person’s risk of premature death, but scientists have yet to find any reason. Now, scientists have discovered one way loneliness can affect a person healthy: Loneliness may cause gene alter its expression in cells, thus reduce a person’s ability to fight with infections.
In a study constitutes 141 elderly people, the researchers investigated the genic expression patterns and relationships of loneliness and leukocytes. 36 of elders were classified as chronic loneliness.The researchers found that compare with non-chronic loneliness people, chronic loneliness ones have more body cells and gene expression of inflammation to fight potential bacterial infection. But ability for cells to fight is reduced.
Psychologist John Cacioppo, who works at University of Chicago said this gene expression patterns makes the body more prone to inflammation than normal. This reaction, at the expense of the cost against the potential virus infection, enhance the organism’s ability to fight bacterial infections.In other words, lonely people has weaker ability to fight against the virus, and their body more good fight bacteria.More importantly, the study found that response patterns of loneliness and inflammatory often occur in pairs, and even they will be spread over time assisted by each other. Depression, stress levels and social support were unable to explain these results.
Researchers in another experiment found a lonely macaques also appeared changes in gene expression patterns of the same inflammatory response. They also found this change associates with its immature mononuclear white blood cells (released by the immune system). These cells are highly inflammatory genic expression levels of the protein, but the genic expression of anti-viral protein is very low.Scientists have found that inflammatory genic expression changes will affect the health of the monkey. When they let the monkey infected with simian immunodeficiency virus, the virus propagate much faster in lonely monkeys than in non-lonely monkey. Cacioppo said: “Lonely monkey have more serious illness than non-lonely monkey.” The researchers also expressed their intention to continue studying how loneliness led to weak people and how to avoid these effects.
This is a very interesting topic, since I want to know how loneliness can affect human. Besides social aspect, now I know it also affects genetically. However, how can our bodies know what is loneliness? I mean, each person view loneliness differently. Some people like to stay alone and they never feel longly. How can this be counted? I think this researchers need to test more group of monkeys in varied conditions. Loneliness is a subjective feeling, and there is no standard to judge it. So in what condition that this feeling would be harmful to human bodies? I hope researchers will figure out eventually through more detailed and more comprehensive further studies.